Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27494018 | 0.83 | CRHBP (0.40) | MEN1KMT2AL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL6678098 | 0.82 | GPR35 (0.39) | GPR35MEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL27402130 | 0.74 | KDM4E (0.39) | KMT2AALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL27479553 | 0.73 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1MAPTGAA | |
| SCHEMBL650892 | 0.70 | MEN1 (0.56) | MEN1KMT2AL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL27477068 | 0.69 | KMT2A (0.49) | KMT2AL3MBTL1ALDH1A1MAPTGAA | |
| SCHEMBL27479894 | 0.69 | ALDH1A1 (0.39) | KMT2AALDH1A1KDM4EMAPTGAA | |
| SCHEMBL6674712 | 0.68 | ALDH1A1 (0.36) | L3MBTL1ALDH1A1KDM4EMAPTGAA | |
| SCHEMBL2362670 | 0.68 | ALDH1A1 (0.50) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL27559510 | 0.68 | CYP1A2 (0.43) | MEN1KMT2AALDH1A1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1310169-A | Anils with nitric oxide synzyme inhibiting function | SHUGAI SEIYAKU K K (JP) | 2001-08-29 | — | — | CN | disclosed |
| CN-1172473-A | Aniline derivatives having nitric oxide synthase inhibitory activity | CHUGAI PHARMACEUTICAL CO LTD (JP) | 1998-02-04 | — | — | CN | disclosed |