Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | DEGS1 | O15121 | 3/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | NQO2 | P16083 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | PEPD | P12955 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL483177 | 0.87 | RAB9A (0.49) | LMNAGAAPOLBALDH1A1KDM4E | |
| SCHEMBL7583871 | 0.85 | NPC1 (0.51) | LMNANPC1POLBALDH1A1MAPT | |
| SCHEMBL7578629 | 0.85 | RAB9A (0.54) | LMNAMAOAMAOBGAANPC1 | |
| SCHEMBL11410940 | 0.85 | NPC1 (0.57) | LMNAGAANPC1POLBALDH1A1 | |
| SCHEMBL28142622 | 0.81 | RAB9A (0.60) | LMNAGAANPC1POLBALDH1A1 | |
| SCHEMBL2701740 | 0.77 | FADS1 (0.53) | LMNANPC1ALDH1A1MAPTKDM4E | |
| SCHEMBL27700592 | 0.76 | KCNQ3 (0.50) | GAANPC1ALDH1A1KMT2AMEN1 | |
| SCHEMBL224092 | 0.74 | HDAC8 (0.46) | LMNAGAAKDM4EKMT2AMEN1 | |
| SCHEMBL8372122 | 0.73 | LMNA (0.52) | LMNAGAANPC1POLBALDH1A1 | |
| SCHEMBL15655870 | 0.72 | RARG (0.59) | ALDH1A1KMT2AMEN1CYP3A4RARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1187185-A | Chalcone retinoids and application method thereof | INST OF MATERIA MEDECA (CN) | 1998-07-08 | — | — | CN | disclosed |