Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.47 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11411879 | 0.88 | CA1 (0.62) | CA1CA2TSHRMAPTRAB9A | |
| SCHEMBL9242685 | 0.85 | RAB9A (0.65) | CA1CA2TSHRMAPTRAB9A | |
| SCHEMBL3842303 | 0.83 | SRD5A2 (0.55) | MAPTL3MBTL1LMNAALDH1A1GAA | |
| SCHEMBL8782253 | 0.82 | SLC6A3 (0.61) | CA1CA2TSHRMAPTRAB9A | |
| SCHEMBL1191950 | 0.82 | TDP1 (0.68) | CA1CA2TSHRMAPTRAB9A | |
| SCHEMBL27449133 | 0.81 | MAPT (0.56) | CA1CA2TSHRMAPTRAB9A | |
| SCHEMBL2457384 | 0.81 | CA1 (0.53) | CA1CA2TSHRMAPTRAB9A | |
| SCHEMBL1339129 | 0.81 | USP2 (0.57) | CA1CA2TSHRMAPTRAB9A | |
| SCHEMBL28276502 | 0.81 | PARP10 (0.67) | CA1CA2TSHRMAPTRAB9A | |
| SCHEMBL28032723 | 0.80 | SRD5A2 (0.56) | MAPTL3MBTL1LMNAALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1154486-C | Method of treating malignant tumours with thyroxine analogues having no significant hormonal activity | �¿���Ĭ�ɷ�����˾ | 2004-06-23 | — | — | CN | disclosed |
| CN-1226826-A | Method for treating malignant tumor with thyroxine analogue without obvious hormone activity | OCTAMER INC (US) | 1999-08-25 | — | — | CN | disclosed |