Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.68 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.52 |
| ▸ | LPAR5 | Q9H1C0 | 3/20 | 0.52 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11411879 | 0.90 | CA1 (0.62) | TDP1L3MBTL1CA1CA2TSHR | |
| SCHEMBL9242685 | 0.86 | RAB9A (0.65) | TDP1L3MBTL1CA1CA2TSHR | |
| SCHEMBL4506078 | 0.84 | PTGS2 (0.56) | TDP1L3MBTL1CA1CA2MAPK14 | |
| SCHEMBL16507459 | 0.83 | LPAR1 (0.80) | TDP1L3MBTL1LPAR1LPAR5 | |
| SCHEMBL8782253 | 0.83 | SLC6A3 (0.61) | TDP1L3MBTL1CA1CA2TSHR | |
| SCHEMBL8746017 | 0.83 | LPAR1 (0.70) | CA1CA2MAPK14LPAR1LPAR5 | |
| SCHEMBL5608673 | 0.83 | HPGD (0.62) | TDP1L3MBTL1MAPK14MAPTRAB9A | |
| SCHEMBL11606972 | 0.83 | PDCD1 (0.55) | TDP1L3MBTL1CA1CA2MAPK14 | |
| SCHEMBL1339129 | 0.82 | USP2 (0.57) | TDP1L3MBTL1CA1CA2TSHR | |
| SCHEMBL28276502 | 0.82 | PARP10 (0.67) | TDP1L3MBTL1CA1CA2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014170842-A2 | SUBSTITUTED ALKYL CARBOXYLIC ACID DERIVATIVES AS GPR AGONISTS | Piramal Enterprises Limited (IN) | 2014-10-23 | — | — | WO | disclosed |
| US-20110046185-A1 | Arylchalcogenoarylalkyl-substituted imidazolidine-2,4-diones, process for preparation thereof, medicaments comprising these compounds and use thereof | SANOFI-AVENTIS (FR) | 2011-02-24 | — | — | US | disclosed |
| US-4098816-A | HYPOGLYCEMIC AGENTS AND ANTILIPEMIC AGENTS | BEECHAM GROUP LIMITED (GB) | 1978-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110046185-A1 | Arylchalcogenoarylalkyl-substituted imidazolidine-2,4-diones, process for preparation thereof, medicaments comprising these compounds and use thereof | PGC, LIPC, CEL | TDP1 3971/4885L3MBTL1 2086/4885CA1 4817/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.