Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPA5 | P11021 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28940718 | 0.91 | HSPA5 (0.48) | HSPA5ALDH1A1HPGDKEAP1L3MBTL1 | |
| SCHEMBL27808570 | 0.87 | ALDH1A1 (0.44) | HSPA5ALDH1A1HPGDL3MBTL1HRH3 | |
| SCHEMBL28343693 | 0.85 | L3MBTL1 (0.53) | ALDH1A1L3MBTL1HRH3HRH1HRH4 | |
| SCHEMBL9130083 | 0.82 | HRH1 (0.52) | HSPA5ALDH1A1HPGDHRH3HRH1 | |
| SCHEMBL30576433 | 0.82 | ALOX5 (0.56) | ALDH1A1L3MBTL1SMN1; SMN2LMNAMAPT | |
| SCHEMBL1846872 | 0.82 | ALOX5 (0.56) | ALDH1A1L3MBTL1SMN1; SMN2LMNAMAPT | |
| SCHEMBL8546939 | 0.82 | MAPT (0.47) | HSPA5ALDH1A1HPGDL3MBTL1HRH3 | |
| SCHEMBL8753243 | 0.79 | HSPA5 (0.52) | HSPA5ALDH1A1HPGDKEAP1HRH1 | |
| SCHEMBL8797884 | 0.79 | HRH1 (0.51) | HSPA5ALDH1A1HPGDHRH3HRH1 | |
| SCHEMBL8745956 | 0.79 | HSPA5 (0.62) | HSPA5ALDH1A1HPGDKEAP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114890941-A | Manganese-based chelate conjugates for MR molecular imaging | 通用医疗公司 | 2022-08-12 | — | — | CN | disclosed |
| CN-114805196-A | Manganese-based chelate conjugates for MR molecular imaging | 通用医疗公司 | 2022-07-29 | — | — | CN | disclosed |
| US-20220168243-A1 | CORONAVIRUS TREATMENT COMPOSITIONS AND METHODS | UNIV NEW YORK STATE RES FOUND (US) | 2022-06-02 | — | — | US | disclosed |
| CN-108136053-B | Manganese-based chelate conjugates for MR molecular imaging | 通用医疗公司 | 2022-05-27 | — | — | CN | disclosed |
| US-8586755-B2 | Substituted nicotinamides as KCNQ2/3 modulators | Grünenthal GmbH (DE) | 2013-11-19 | — | — | US | disclosed |
| US-20120184550-A1 | SUBSTITUTED NICOTINAMIDES AS KCNQ2/3 MODULATORS | GRUNENTHAL GMBH (DE) | 2012-07-19 | — | — | US | disclosed |
| US-8178684-B2 | Substituted nicotinamides as KCNQ2/3 modulators | GRUENENTHAL GMBH (DE) | 2012-05-15 | — | — | US | disclosed |
| US-20100234429-A1 | SUBSTITUTED NICOTINAMIDES AS KCNQ2/3 MODULATORS | Grünenthal GmbH (DE) | 2010-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120184550-A1 | SUBSTITUTED NICOTINAMIDES AS KCNQ2/3 MODULATORS | KCNQ2, KCNQ1, KCNQ3 | HSPA5 3501/4885ALDH1A1 2196/4885HPGD 651/4885 |
| US-20220168243-A1 | CORONAVIRUS TREATMENT COMPOSITIONS AND METHODS | ACE, SARS1, ACE2 | HSPA5 4345/4885ALDH1A1 4521/4885HPGD 3801/4885 |
| US-20100234429-A1 | SUBSTITUTED NICOTINAMIDES AS KCNQ2/3 MODULATORS | KCNQ1, KCNQ2, KCNQ3 | HSPA5 3237/4885ALDH1A1 3206/4885HPGD 508/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.