Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPA5 | P11021 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11064066 | 0.83 | HSPA5 (0.58) | HSPA5ALDH1A1HPGDKEAP1CYP2D6 | |
| SCHEMBL9752017 | 0.79 | ALDH1A1 (0.59) | HSPA5ALDH1A1HPGDKEAP1CYP2D6 | |
| SCHEMBL2750237 | 0.79 | HSPA5 (0.58) | HSPA5ALDH1A1HPGDKEAP1TAAR1 | |
| SCHEMBL29357407 | 0.78 | HSPA5 (1.00) | HSPA5ALDH1A1HPGDKEAP1CYP2D6 | |
| SCHEMBL49745 | 0.78 | HSPA5 (1.00) | HSPA5ALDH1A1HPGDKEAP1CYP2D6 | |
| SCHEMBL27460114 | 0.76 | HSPA5 (0.59) | HSPA5ALDH1A1HPGDKEAP1CYP2D6 | |
| SCHEMBL21387079 | 0.76 | HSPA5 (0.59) | HSPA5ALDH1A1HPGDKEAP1CYP2D6 | |
| SCHEMBL29839938 | 0.76 | HSPA5 (0.94) | HSPA5ALDH1A1HPGDKEAP1CYP2D6 | |
| SCHEMBL7809667 | 0.76 | HSPA5 (0.94) | HSPA5ALDH1A1HPGDKEAP1CYP2D6 | |
| Ammonia Solution, Strong SCHEMBL28323965 | 0.76 | HSPA5 (0.94) | HSPA5ALDH1A1HPGDKEAP1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118834847-A | ALS mutant protein of rice, coding gene and application thereof | 合肥戬谷生物科技有限公司 | 2024-10-25 | — | — | CN | claimed |
| CN-118834847-A | ALS mutant protein of rice, coding gene and application thereof | 合肥戬谷生物科技有限公司 | 2024-10-25 | — | — | CN | disclosed |
| US-5672567-A | PRE- AND POST-EMERGENCE | ZENECA LIMITED (GB) | 1997-09-30 | — | — | US | disclosed |
| US-5670453-A | PYRAZINEARYL COMPOUND | ZENECA LIMITED (GB) | 1997-09-23 | — | — | US | disclosed |
| EP-0758323-A1 | HERBICIDAL HYDROXYBENZYL-SUBSTITUTED HETEROARYL COMPOUNDS AND DERIVATIVES THEREOF | ZENECA LIMITED (GB) | 1997-02-19 | — | — | EP | disclosed |
| WO-1995029898-A1 | HERBICIDAL HYDROXYBENZYL-SUBSTITUTED HETEROARYL COMPOUNDS AND DERIVATIVES THEREOF | ZENECA LIMITED (GB) | 1995-11-09 | — | — | WO | disclosed |
| US-4116958-A | ORGANIC SYNTHETIC METHODS BENZYLPYRIMIDINE DERIVATIVES | BURROUGHS WELLCOME CO. (US) | 1978-09-26 | — | — | US | disclosed |