Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.40 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.39 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.39 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MC4R | P32245 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | MC3R | P41968 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34651 | 0.88 | — | — | |
| SCHEMBL9786602 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL4023730 | 0.86 | NPC1 (0.47) | NPC1RAB9ATBXAS1CSNK1A1TYRO3 | |
| Hydrochloric Acid SCHEMBL4244388 | 0.86 | — | — | |
| Malonic Acid SCHEMBL28603419 | 0.85 | NPC1 (0.43) | NPC1RAB9ATBXAS1KMT2AKDM4E | |
| Pyrrole SCHEMBL1577642 | 0.83 | CSNK1A1 (0.44) | NPC1RAB9ATBXAS1CSNK1A1TYRO3 | |
| Butyric Acid SCHEMBL2453570 | 0.83 | TBXAS1 (0.43) | NPC1RAB9ATBXAS1CSNK1A1TYRO3 | |
| Pyridine SCHEMBL6603891 | 0.81 | CSNK1A1 (0.42) | NPC1RAB9ATBXAS1CSNK1A1TYRO3 | |
| Pyridine SCHEMBL9978894 | 0.81 | CSNK1A1 (0.42) | NPC1RAB9ATBXAS1CSNK1A1TYRO3 | |
| Maleic Acid SCHEMBL27580931 | 0.81 | RAB9A (0.41) | NPC1RAB9ATBXAS1CSNK1A1TYRO3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1228695-A | Substituted 1,2,3,4-tetrahydro-2-dibenzofuranamines and 2-aminocyclohepta [b] benzofurans | LILLY CO ELI (US) | 1999-09-15 | — | — | CN | disclosed |