Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.43 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.36 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.36 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | TLK2 | Q86UE8 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hexanoate SCHEMBL9359564 | 0.89 | TBXAS1 (0.50) | TBXAS1KMT2AXDHPDE4AALDH1A1 | |
| Decanoic Acid SCHEMBL9359579 | 0.88 | TBXAS1 (0.52) | TBXAS1KMT2AXDHPDE4AALDH1A1 | |
| Malonic Acid SCHEMBL27504201 | 0.83 | NPC1 (0.41) | TBXAS1HDAC1NPC1RAB9ACSNK1A1 | |
| SCHEMBL9786602 | 0.80 | — | — | |
| Butyric Acid SCHEMBL27654245 | 0.78 | ALDH1A1 (0.57) | TBXAS1FFAR3HDAC3HDAC1HDAC2 | |
| Pyrrole SCHEMBL1577642 | 0.78 | CSNK1A1 (0.44) | TBXAS1NPC1RAB9ACSNK1A1TYRO3 | |
| SCHEMBL7574578 | 0.78 | NPC1 (0.46) | TBXAS1NPC1RAB9AKMT2ATLK2 | |
| Butyric Acid SCHEMBL28994918 | 0.77 | TBXAS1 (0.57) | TBXAS1FFAR3HDAC3HDAC1HDAC2 | |
| SCHEMBL27936752 | 0.76 | NPC1 (0.45) | HDAC1NPC1RAB9ACSNK1A1TYRO3 | |
| Pyridine SCHEMBL6603891 | 0.76 | CSNK1A1 (0.42) | TBXAS1NPC1RAB9ACSNK1A1TYRO3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110295014-A1 | PROCESS FOR PRODUCTION OF PIPERIDINE DERIVATIVES | ALBANY MOLECULAR RESEARCH, INC. (US) | 2011-12-01 | — | — | US | disclosed |
| US-8022220-B2 | Process for production of piperidine derivatives | ALBANY MOLECULAR RESEARCH, INC. (US) | 2011-09-20 | — | — | US | disclosed |
| US-20100010227-A1 | PROCESS FOR PRODUCTION OF PIPERIDINE DERIVATIVES | ALBANY MOLECULAR RESEARCH, INC. (US) | 2010-01-14 | — | — | US | disclosed |
| US-7560561-B2 | Process for production of piperidine derivatives | ALBANY MOLECULAR RESEARCH, INC. (US) | 2009-07-14 | — | — | US | disclosed |
| EP-0877733-B1 | PROCESS FOR PRODUCTION OF PIPERIDINE DERIVATIVES | AMR TECHNOLOGY INC (US) | 2006-08-09 | — | — | EP | disclosed |
| US-6974872-B2 | Process for production of piperidine derivatives | AMR TECHNOLOGY, INC. (US) | 2005-12-13 | — | — | US | disclosed |
| US-20050272771-A1 | Process for production of piperidine derivatives | AMR TECHNOLOGY, INC. (US) | 2005-12-08 | — | — | US | disclosed |
| EP-1362849-A2 | Process for production of piperidine derivatives | ALBANY MOLECULAR RESEARCH, INC. (US) | 2003-11-19 | — | — | EP | disclosed |
| US-20030171590-A1 | Process for production of piperidine derivatives | APOLLO ADMINISTRATIVE AGENCY LLC, AS SUCCESSOR AGENT | 2003-09-11 | — | — | US | disclosed |
| US-6452011-B1 | NON-SEDATING ANTI-HISTAMINE H1 ANTAGONIST | ALBANY MOLECULAR RESEARCH, INC. | 2002-09-17 | — | — | US | disclosed |
| US-6448406-B1 | IMPROVED PROCESS FOR PREPARATION OF TERFENADINE CARBOXYLIC ACID METABOLITE AND CAREBASTINE DERIVATIVES; HISTAMINE H1 RECEPTOR BLOCKING AND CALCIUM ANTAGONISTS; RESPIRATORY, ALLERGIC, AND CARDIOVASCULAR DISEASE STATES | ALBANY MOLECULAR RESEARCH, INC. | 2002-09-10 | — | — | US | disclosed |
| US-6201124-B1 | CONVERTING, WITH A PIPERIDINE COMPOUND, REGIOISOMERS UNDER NON-FRIEDEL-CRAFTS REACTION CONDITIONS | ALBANY MOLECULAR RESEARCH, INC. | 2001-03-13 | — | — | US | disclosed |
| EP-0877733-A4 | PROCESS FOR PRODUCTION OF PIPERIDINE DERIVATIVES | ALBANY MOLECULAR RES INC (US) | 1999-03-31 | — | — | EP | disclosed |
| EP-0877733-A1 | PROCESS FOR PRODUCTION OF PIPERIDINE DERIVATIVES | ALBANY MOLECULAR RESEARCH, INC. (US) | 1998-11-18 | — | — | EP | disclosed |
| WO-1997022344-A1 | PROCESS FOR PRODUCTION OF PIPERIDINE DERIVATIVES | ALBANY MOLECULAR RESEARCH, INC. (US) | 1997-06-26 | — | — | WO | disclosed |
| EP-0402469-B1 | CATECHOL COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL PREPARATION CONTAINING SAME | TERUMO CORP (JP) | 1994-06-01 | — | — | EP | disclosed |
| EP-0402469-A1 | CATECHOL COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL PREPARATION CONTAINING SAME | TERUMO KABUSHIKI KAISHA (JP) | 1990-12-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110295014-A1 | PROCESS FOR PRODUCTION OF PIPERIDINE DERIVATIVES | OR10J3, NR1H2, NR1H3 | TBXAS1 1703/4885FFAR3 604/4885HDAC3 326/4885 |
| US-20050272771-A1 | Process for production of piperidine derivatives | HRH4, CBR1, CBR3 | TBXAS1 1833/4885FFAR3 999/4885HDAC3 389/4885 |
| US-20030171590-A1 | Process for production of piperidine derivatives | NR4A1, NR4A2, NR5A2 | TBXAS1 1168/4885FFAR3 1329/4885HDAC3 162/4885 |
| US-20100010227-A1 | PROCESS FOR PRODUCTION OF PIPERIDINE DERIVATIVES | DDC, HPD, ALDH7A1 | TBXAS1 2695/4885FFAR3 1698/4885HDAC3 457/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.