Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4039230 | 0.84 | PAX8 (0.35) | PAX8BRD4IRAK4 | |
| SCHEMBL4040622 | 0.81 | CYP1A2 (0.41) | PAX8ALDH1A1LMNAKMT2A | |
| SCHEMBL3484770 | 0.79 | KMT2A (0.50) | PAX8BRD4HTR2CSLC6A4LMNA | |
| SCHEMBL31709504 | 0.79 | PAX8 (0.37) | PAX8BRD4LMNAKMT2A | |
| SCHEMBL12675260 | 0.79 | PAX8 (0.37) | PAX8BRD4L3MBTL1LMNAKMT2A | |
| SCHEMBL12853542 | 0.77 | KDM4E (0.46) | PAX8BRD4IRAK4KDM4EL3MBTL1 | |
| SCHEMBL691501 | 0.73 | HCAR3 (0.51) | PAX8GPR119KDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL7790318 | 0.73 | PAX8 (0.43) | PAX8BRD4GPR119KDM4EL3MBTL1 | |
| SCHEMBL11508947 | 0.73 | NPC1 (0.46) | KDM4EL3MBTL1ALDH1A1LMNAKMT2A | |
| SCHEMBL30802108 | 0.71 | PAX8 (0.37) | PAX8BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1210267-C | 2-hydroxy-mutilin carbamate derivatives for antibacterial use | SMITHKLINE BEECHAM PLC (GB) | 2005-07-13 | — | — | CN | disclosed |
| CN-1427827-A | 2-Hydroxy-mutilin carbamate derivatives for antibacterial use | SMITHKLINE BEECHAM PLC (GB) | 2003-07-02 | — | — | CN | disclosed |