Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MPL | P40238 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 5/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.34 |
| ▸ | NPC1 | O15118 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.33 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.32 |
| ▸ | GUSB | P08236 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27506102 | 0.81 | ALOX5 (0.46) | ALDH1A1KDM4ERAB9ANPC1MAPT | |
| SCHEMBL27531535 | 0.80 | ALDH1A1 (0.42) | ALDH1A1KDM4ERAB9ASMN1; SMN2NPC1 | |
| SCHEMBL27491448 | 0.77 | TRPM8 (0.47) | KDM4ESMN1; SMN2 | |
| SCHEMBL27492138 | 0.76 | KDM4E (0.47) | ALDH1A1KDM4ERAB9ANPC1MEN1 | |
| SCHEMBL27491451 | 0.75 | KDM4E (0.50) | ALDH1A1KDM4ERAB9ASMN1; SMN2NPC1 | |
| SCHEMBL27505330 | 0.75 | KDM4E (0.49) | ALDH1A1KDM4ERAB9ASMN1; SMN2NPC1 | |
| SCHEMBL27507729 | 0.74 | PDPK1 (0.40) | RAB9A | |
| SCHEMBL27505716 | 0.72 | ALOX5 (0.36) | RAB9AGAA | |
| SCHEMBL27490767 | 0.72 | PDPK1 (0.36) | ALDH1A1KDM4ESMN1; SMN2MAPTGAA | |
| SCHEMBL27505331 | 0.72 | MAOA (0.34) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1204323-A | Use of tricyclic 1,4-dihydro-1,4-dioxo-1 H-naphthalene derivatives, resulting novel compounds and therapeutical use thereof | INNOTHERA LAB SA (FR) | 1999-01-06 | — | — | CN | disclosed |