Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 known ✓ | P35228 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL27827142 | 0.87 | NOS2 (0.30) | NOS2 | |
| Acetic Acid SCHEMBL27943542 | 0.73 | KMT2A (0.31) | — | |
| Acetic Acid SCHEMBL27482834 | 0.71 | FFAR3 (0.41) | — | |
| Propene SCHEMBL27710736 | 0.69 | TP53 (0.35) | — | |
| Urea SCHEMBL2033880 | 0.69 | TP53 (0.38) | NOS2 | |
| Urea SCHEMBL2222199 | 0.69 | TP53 (0.38) | NOS2 | |
| SCHEMBL27505903 | 0.69 | KMT2A (0.33) | — | |
| SCHEMBL27669545 | 0.69 | KMT2A (0.33) | — | |
| SCHEMBL27527479 | 0.69 | ALDH1A1 (0.32) | — | |
| Propionamide SCHEMBL27471373 | 0.67 | CHRNB2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1297619-C | Hydrophilicity-promoting and hydrophilicity-maintaining agent for polysilazane-containing coating film | CLARIANT INT LTD (CH) | 2007-01-31 | — | — | CN | claimed |
| CN-1653153-A | Hydrophilicity-promoting and hydrophilicity-maintaining agent for polysilazane-containing coating film | CLARIANT INT LTD (CH) | 2005-08-10 | — | — | CN | claimed |
| CN-1297619-C | Hydrophilicity-promoting and hydrophilicity-maintaining agent for polysilazane-containing coating film | CLARIANT INT LTD (CH) | 2007-01-31 | — | — | CN | disclosed |
| CN-1242044-C | Powder detergent | KOMETAISAD CO LTD (JP) | 2006-02-15 | — | — | CN | disclosed |
| CN-1653153-A | Hydrophilicity-promoting and hydrophilicity-maintaining agent for polysilazane-containing coating film | CLARIANT INT LTD (CH) | 2005-08-10 | — | — | CN | disclosed |
| CN-1388236-A | Powder detergent | KOMETAISAD CO LTD (JP) | 2003-01-01 | — | — | CN | disclosed |