Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 known ✓ | P35228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL27508134 | 0.87 | NOS2 (0.31) | NOS2 | |
| Bicarbonate SCHEMBL4950236 | 0.76 | ALDH1A1 (0.31) | — | |
| Acetic Acid SCHEMBL2462226 | 0.74 | ALDH1A1 (0.30) | — | |
| Acetic Acid SCHEMBL28138856 | 0.73 | — | — | |
| Acetic Acid SCHEMBL27394038 | 0.72 | — | — | |
| SCHEMBL1479710 | 0.70 | — | — | |
| SCHEMBL4241571 | 0.69 | — | — | |
| SCHEMBL4449114 | 0.69 | — | — | |
| SCHEMBL10930795 | 0.68 | ALDH1A1 (0.35) | — | |
| SCHEMBL5454171 | 0.67 | ALDH1A1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102222535-B | The manufacture method of electric conduction powder, conductive material containing this electric conduction powder and conductive particle | NIPPON CHEMICAL INDUSTRY CO., LTD. (JP) | 2015-08-26 | — | — | CN | disclosed |
| CN-102187405-B | Conductive powder, conductive material containing the same, and method for producing conductive particles | NIPPON CHEMICAL IND | 2013-01-02 | — | — | CN | disclosed |
| CN-102222535-A | Electric conduction powder body, electric conduction material having the electric conduction powder body and manufacturing method of electric conduction particles | NIPPON CHEMICAL IND | 2011-10-19 | — | — | CN | disclosed |
| CN-102187405-A | Conductive powder, conductive material containing the same, and method for producing conductive particles | NIPPON CHEMICAL IND | 2011-09-14 | — | — | CN | disclosed |