Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 1/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.39 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 3/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CTRC | Q99895 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | AXL | P30530 | 3/20 | 0.37 |
| ▸ | SGK1 | O00141 | 1/20 | 0.37 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27588723 | 0.87 | HPGDS (0.46) | LMNAKDM4EMAPK1L3MBTL1 | |
| SCHEMBL948199 | 0.85 | KDM4E (0.50) | PIN1LMNAKDM4ETP53MAPK1 | |
| SCHEMBL15758954 | 0.81 | ALPL (0.45) | LMNAKDM4EMAPK1TDP1L3MBTL1 | |
| SCHEMBL27527064 | 0.79 | DHODH (0.38) | TPMTHCAR1DHODHPTGDR2LMNA | |
| SCHEMBL15510700 | 0.78 | KDM4E (0.40) | PIN1LMNAKDM4EMAPK1CAMKK2 | |
| SCHEMBL27579261 | 0.78 | TPMT (0.43) | TPMTHCAR1DHODHLMNAKDM4E | |
| SCHEMBL3383809 | 0.77 | KDM4E (0.46) | PIN1PTGDR2LMNAKDM4ETP53 | |
| SCHEMBL16109091 | 0.75 | KDM4E (0.36) | PIN1LMNAKDM4ETP53MAPK1 | |
| SCHEMBL27817794 | 0.75 | TPMT (0.40) | TPMTHCAR1DHODHLMNAKDM4E | |
| SCHEMBL28192178 | 0.73 | PIN1 (0.56) | PIN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1167486-A | 2- (pyrazol-3-yl) carbapenem derivatives | SMITHKLINE BEECHAM PLC (GB) | 1997-12-10 | — | — | CN | disclosed |