Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.69 |
| ▸ | BACE1 | P56817 | 4/20 | 0.69 |
| ▸ | AURKA | O14965 | 4/20 | 0.54 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.53 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | DRD4 | P21917 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11787696 | 0.81 | TNF (0.49) | ACHEBACE1AURKADRD2DRD4 | |
| SCHEMBL4774035 | 0.80 | ACHE (0.60) | ACHEBACE1TLR9TLR7KDM4E | |
| SCHEMBL6232120 | 0.80 | HRH4 (0.62) | ACHEDRD4MAPTNPSR1KDM4E | |
| SCHEMBL3684760 | 0.80 | HTR3E (0.53) | ACHEBACE1DRD4MAPTKDM4E | |
| SCHEMBL2924047 | 0.79 | PDGFRB (0.73) | — | |
| SCHEMBL27111611 | 0.78 | AURKA (0.48) | ACHEBACE1AURKADRD2DRD4 | |
| SCHEMBL3685933 | 0.78 | LMNA (0.48) | ACHEBACE1TLR9TLR7MAPT | |
| SCHEMBL31502039 | 0.76 | ENPP1 (0.48) | ACHEBACE1AURKADRD2DRD4 | |
| SCHEMBL20813430 | 0.76 | ENPP1 (0.48) | ACHEBACE1AURKADRD2DRD4 | |
| SCHEMBL2919337 | 0.76 | NCF1 (0.60) | TLR9TLR7MAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1169795-C | Nitrogenous heterocyclic compounds | Э�ͷ���ҵ��ʽ���� | 2004-10-06 | — | — | CN | disclosed |
| CN-1208404-A | Nitrogenous heterocyclic compounds | KYOWA HAKKO KOGYO KK (JP) | 1999-02-17 | — | — | CN | disclosed |