Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.57 |
| ▸ | CCR1 | P32246 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | CCR5 | P51681 | 1/20 | 0.56 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 8-Hydroxy Quinaldine SCHEMBL1147958 | 0.96 | METAP2 (0.53) | METAP2CCR1RAB9ACCR5PARP1 | |
| 8-Hydroxy Quinaldine SCHEMBL6364851 | 0.96 | METAP2 (0.53) | METAP2CCR1RAB9ACCR5PARP1 | |
| 8-Hydroxy Quinaldine SCHEMBL31268359 | 0.96 | METAP2 (0.57) | METAP2CCR1RAB9ACCR5PARP1 | |
| 8-Hydroxy Quinaldine SCHEMBL1133461 | 0.96 | METAP2 (0.57) | METAP2CCR1RAB9ACCR5PARP1 | |
| 8-Hydroxy Quinaldine SCHEMBL28411870 | 0.96 | METAP2 (0.57) | METAP2CCR1RAB9ACCR5PARP1 | |
| 8-Hydroxy Quinaldine SCHEMBL546578 | 0.96 | METAP2 (0.57) | METAP2CCR1RAB9ACCR5PARP1 | |
| 8-Hydroxy Quinaldine SCHEMBL546344 | 0.96 | METAP2 (0.57) | METAP2CCR1RAB9ACCR5PARP1 | |
| 8-Hydroxy Quinaldine SCHEMBL2059590 | 0.96 | METAP2 (0.57) | METAP2CCR1RAB9ACCR5PARP1 | |
| 8-Hydroxy Quinaldine SCHEMBL1714719 | 0.96 | METAP2 (0.57) | METAP2CCR1RAB9ACCR5PARP1 | |
| 8-Hydroxy Quinaldine SCHEMBL1715251 | 0.96 | METAP2 (0.57) | METAP2CCR1RAB9ACCR5PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1486549-B1 | ORGANIC ELECTROLUMINESCENT ELEMENT | TOYOTA JIDOSHOKKI KK (JP) | 2012-01-11 | — | — | EP | disclosed |
| EP-1755362-B1 | ORGANIC EL DEVICE | TOYOTA JIDOSHOKKI KK (JP) | 2011-07-20 | — | — | EP | disclosed |
| US-7854998-B2 | Organic EL devices | KABUSHIKI KAISHA TOYOTA JIDOSHOKKI (JP) | 2010-12-21 | — | — | US | disclosed |
| EP-1489154-B1 | ORGANIC ELECTROLUMINESCENCE DEVICE | TOYOTA JIDOSHOKKI KK (JP) | 2009-05-13 | — | — | EP | disclosed |
| US-7521567-B2 | Amine compound and uses thereof | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2009-04-21 | — | — | US | disclosed |
| US-20080290788-A1 | Organic el Devices | KABUSHIKI KAISHA TOYOTA JIDOSHOKKI (JP) | 2008-11-27 | — | — | US | disclosed |
| US-7419727-B2 | Organic electroluminescent device | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2008-09-02 | — | — | US | disclosed |
| US-7338720-B2 | Organic electroluminescent element | KABUSHIKI KAISHA TOYOTA JIDOSHOKKI (JP) | 2008-03-04 | — | — | US | disclosed |
| US-7252892-B2 | Organic electroluminescence device | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2007-08-07 | — | — | US | disclosed |
| EP-1755362-A1 | ORGANIC EL DEVICE | KABUSHIKI KAISHA TOYOTA JIDOSHOKKI (JP) | 2007-02-21 | — | — | EP | disclosed |
| US-20070018568-A1 | Organic electroluminescent device | KABUSHIKI KAISHA TOYOTA JIDOSHOKKI (JP) | 2007-01-25 | — | — | US | disclosed |
| US-20060228577-A1 | Organic electroluminescent device | KABUSHIKI KAISHA TOYOTA JIDOSHOKKI (JP) | 2006-10-12 | — | — | US | disclosed |
| US-20060226421-A1 | Amine compound and uses thereof | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KENKYUJO (JP) | 2006-10-12 | — | — | US | disclosed |
| US-20060192473-A1 | Organic electroluminescent device | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2006-08-31 | — | — | US | disclosed |
| EP-1599074-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | Kabushiki Kaisha Toyota Jidoshokki (JP) | 2005-11-23 | — | — | EP | disclosed |
| EP-1560469-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | Kabushiki Kaisha Toyota Jidoshokki (JP) | 2005-08-03 | — | — | EP | disclosed |
| US-20050089713-A1 | Organic electroluminescent element | KABUSHIKI KAISHA TOYOTA JIDOSHOKKI (JP) | 2005-04-28 | — | — | US | disclosed |
| US-20050084707-A1 | Organic electroluminescence device | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2005-04-21 | — | — | US | disclosed |
| EP-1489154-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo (JP) | 2004-12-22 | — | — | EP | disclosed |
| EP-1486549-A1 | ORGANIC ELECTROLUMINESCENT ELEMENT | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo (JP) | 2004-12-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060226421-A1 | Amine compound and uses thereof | PNMT, TYR, PAM | METAP2 560/4885CCR1 4017/4885RAB9A 2372/4885 |
| US-20050084707-A1 | Organic electroluminescence device | ELAVL1, SELE, CELF2 | METAP2 4464/4885CCR1 4055/4885RAB9A 4324/4885 |
| US-20050089713-A1 | Organic electroluminescent element | SOD3, CELF2, SOD1 | METAP2 4353/4885CCR1 4096/4885RAB9A 4581/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.