Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.61 |
| ▸ | CTSL | P07711 | 3/20 | 0.61 |
| ▸ | CTSB | P07858 | 2/20 | 0.61 |
| ▸ | CTSS | P25774 | 2/20 | 0.61 |
| ▸ | CNR2 | P34972 | 2/20 | 0.51 |
| ▸ | GRN | P28799 | 1/20 | 0.50 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.50 |
| ▸ | CCR1 | P32246 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8742431 | 0.91 | ALDH1A1 (0.54) | CTSKCTSLCTSBCTSSGRN | |
| SCHEMBL8742462 | 0.82 | GRN (0.71) | CTSKCTSLCTSBCTSSCNR2 | |
| SCHEMBL7463178 | 0.75 | GRN (0.68) | GRNSORT1CCR1PSMB5 | |
| SCHEMBL3359427 | 0.75 | CCR1 (0.54) | CTSKCTSLCTSBCTSSGRN | |
| SCHEMBL7392749 | 0.75 | ALDH1A1 (0.58) | ALDH1A1GAAMAPTHDAC8HDAC1 | |
| SCHEMBL6443604 | 0.75 | ALDH1A1 (0.58) | ALDH1A1GAAMAPTHDAC8HDAC1 | |
| SCHEMBL5829481 | 0.74 | HDAC8 (0.55) | ALDH1A1GAAMAPTHDAC8HPGD | |
| SCHEMBL7468748 | 0.74 | ALDH1A1 (0.54) | CTSKCTSLCTSBCTSSGRN | |
| SCHEMBL7517851 | 0.74 | CTSK (0.63) | CTSKCTSLCTSBCTSSUTS2R | |
| SCHEMBL27348044 | 0.74 | KDM4C (0.52) | ALDH1A1GAAMAPTHDAC8HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1255162-A | Protease inhibitors | SMITHKLINE BEECHAM CORP (US) | 2000-05-31 | — | — | CN | claimed |
| CN-1255162-A | Protease inhibitors | SMITHKLINE BEECHAM CORP (US) | 2000-05-31 | — | — | CN | disclosed |