Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 3/20 | 0.53 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.49 |
| ▸ | HRH1 | P35367 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9079346 | 0.93 | LTB4R (0.46) | LTB4RTBXAS1HRH1LMNAMAPT | |
| SCHEMBL27498072 | 0.86 | TSHR (0.49) | TBXAS1LMNAMAPTMAPK1ALDH1A1 | |
| SCHEMBL17027841 | 0.85 | LTB4R (0.68) | LTB4RLMNAMAPTALDH1A1TRPA1 | |
| SCHEMBL6971015 | 0.85 | LTB4R (0.68) | LTB4RLMNAMAPTALDH1A1TRPA1 | |
| SCHEMBL17027837 | 0.85 | LTB4R (0.68) | LTB4RLMNAMAPTALDH1A1TRPA1 | |
| SCHEMBL6344592 | 0.85 | LTB4R (0.68) | LTB4RLMNAMAPTALDH1A1TRPA1 | |
| SCHEMBL7385392 | 0.83 | LTB4R (0.66) | LTB4RLMNAMAPTMAPK1ALDH1A1 | |
| SCHEMBL27534729 | 0.82 | TBXAS1 (0.62) | LTB4RTBXAS1HRH1 | |
| SCHEMBL27255501 | 0.81 | HRH1 (0.51) | HRH1 | |
| SCHEMBL5067240 | 0.81 | LTB4R (0.53) | LTB4RALDH1A1ACE2LTA4HTRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1224624-C | 1, 8-naphthyridin-2 (1H) -one derivatives | GRELAN PHARMACEUTICAL CO (JP) | 2005-10-26 | — | — | CN | disclosed |
| CN-1407984-A | Novel 1, 8-naphthyridin-2 (1H) -one derivatives | GRELAN PHARMACEUTICAL CO (JP) | 2003-04-02 | — | — | CN | disclosed |