Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.46 |
| ▸ | TSPO | P30536 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | MMP9 | P14780 | 2/20 | 0.42 |
| ▸ | MMP8 | P22894 | 2/20 | 0.42 |
| ▸ | MMP12 | P39900 | 2/20 | 0.42 |
| ▸ | MMP13 | P45452 | 2/20 | 0.42 |
| ▸ | MMP14 | P50281 | 2/20 | 0.42 |
| ▸ | MMP16 | P51512 | 2/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3817959 | 0.98 | PTGS1 (0.54) | PTGS1LMNAL3MBTL1PTGS2POLB | |
| SCHEMBL8875079 | 0.98 | PTGS1 (0.54) | PTGS1LMNAL3MBTL1PTGS2POLB | |
| SCHEMBL1345669 | 0.98 | PTGS1 (0.54) | PTGS1LMNAL3MBTL1PTGS2POLB | |
| SCHEMBL27638955 | 0.89 | LTA4H (0.47) | PTGS1LMNAL3MBTL1PTGS2POLB | |
| SCHEMBL11826285 | 0.87 | HTR2A (0.60) | PTGS1L3MBTL1PTGS2HTR2ASLC6A4 | |
| SCHEMBL10956995 | 0.87 | PTGS1 (0.44) | PTGS1LMNAL3MBTL1PTGS2POLB | |
| SCHEMBL1685873 | 0.85 | CTNNB1 (0.53) | PTGS1LMNAL3MBTL1POLBCTNNB1 | |
| SCHEMBL11191908 | 0.84 | PTGS1 (0.51) | PTGS1LMNAL3MBTL1PTGS2POLB | |
| SCHEMBL10937637 | 0.83 | LMNA (0.51) | PTGS1LMNAL3MBTL1PTGS2POLB | |
| SCHEMBL28580702 | 0.82 | PTGS2 (0.55) | PTGS1LMNAPTGS2MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1315856-A | Therapeutic methods employing disulfide derivatives of dithiocarbamates and compositions useful therefor | MEDINOX INC (US) | 2001-10-03 | — | — | CN | disclosed |
| CN-1230178-A | Polydithiocarbamate-containing macromolecules and use thereof for therapeutic and diagnostic applications | MEDINOX INC (US) | 1999-09-29 | — | — | CN | disclosed |
| CN-1228697-A | Method for in vivo reduction of iron levels and compositions useful therefor | MEDINOX INC (US) | 1999-09-15 | — | — | CN | disclosed |