Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | HTR2C | P28335 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | CCL2 | P13500 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7760865 | 0.86 | SIGMAR1 (0.32) | SIGMAR1HTR6HTR2AHTR2C | |
| SCHEMBL2830663 | 0.85 | HTR2C (0.37) | SIGMAR1HTR6HTR2AHTR2CTSHR | |
| SCHEMBL6055955 | 0.84 | HTR2C (0.40) | SIGMAR1HTR6HTR2AHTR2CTSHR | |
| SCHEMBL2962881 | 0.79 | HTR6 (0.31) | HTR6HTR2A | |
| SCHEMBL2958995 | 0.77 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL8601261 | 0.77 | CYP1A2 (0.42) | ALDH1A1TSHRACHEKDM4ELMNA | |
| SCHEMBL2970857 | 0.77 | CYP1A2 (0.37) | ALDH1A1 | |
| SCHEMBL2962326 | 0.76 | NQO2 (0.33) | HTR6HTR2A | |
| SCHEMBL2962850 | 0.76 | CYP1A2 (0.32) | ALDH1A1 | |
| SCHEMBL2969302 | 0.75 | SIGMAR1 (0.31) | SIGMAR1HTR6HTR2ARET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1198835-C | Bridged metallocene complex for (CO) polymerization of olefins | ENICHEM SPA (IT) | 2005-04-27 | — | — | CN | disclosed |
| CN-1239098-A | Bridged metallocene complex for (CO) polymerization of olefins | ENICHEM SPA (IT) | 1999-12-22 | — | — | CN | disclosed |