Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 1/20 | 0.42 |
| ▸ | RARG | P13631 | 8/20 | 0.41 |
| ▸ | RARB | P10826 | 7/20 | 0.41 |
| ▸ | TP53 | P04637 | 4/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | RARA | P10276 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9317943 | 0.82 | WDR5 (0.51) | WDR5RARGRARBTP53SMN1; SMN2 | |
| SCHEMBL7744702 | 0.79 | RARB (0.58) | WDR5RARGRARBTP53SMN1; SMN2 | |
| SCHEMBL9318192 | 0.76 | MEN1 (0.46) | WDR5RARGRARBTP53DHODH | |
| SCHEMBL4747624 | 0.76 | RARB (0.61) | WDR5RARGRARBTP53DHODH | |
| SCHEMBL30011654 | 0.76 | RARG (0.68) | RARGRARBTP53SMN1; SMN2RARA | |
| SCHEMBL3813305 | 0.76 | RARG (0.68) | RARGRARBTP53SMN1; SMN2RARA | |
| SCHEMBL8322288 | 0.74 | RARB (0.49) | WDR5RARGRARBTP53DHODH | |
| SCHEMBL8766629 | 0.73 | RARB (0.42) | WDR5RARGRARBTP53DHODH | |
| SCHEMBL9318235 | 0.72 | RARB (0.48) | WDR5RARGRARBTP53DHODH | |
| SCHEMBL9318119 | 0.72 | RARB (0.44) | WDR5RARGRARBTP53DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1279902-C | Apoptosis-inducing adamantyl derivatives and their use in the preparation of anti-cancer drugs | GALDERMA RECH S DERMATOLOGIQUE (FR) | 2006-10-18 | — | — | CN | disclosed |
| CN-1230111-A | Apoptosis inducing adamantyl derivatives and their usage as anti-cancer agents | GALDERMA RES & DEV (FR) | 1999-09-29 | — | — | CN | disclosed |