Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 6/20 | 0.61 |
| ▸ | RARG | P13631 | 6/20 | 0.61 |
| ▸ | RARA | P10276 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | PGR | P06401 | 1/20 | 0.61 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.61 |
| ▸ | GOT1 | P17174 | 1/20 | 0.61 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8322288 | 0.90 | RARB (0.49) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL9317943 | 0.88 | WDR5 (0.51) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL9318241 | 0.88 | RARB (0.48) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL9318192 | 0.88 | MEN1 (0.46) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL9318235 | 0.85 | RARB (0.48) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL7744702 | 0.85 | RARB (0.58) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL9318119 | 0.85 | RARB (0.44) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL9317799 | 0.83 | RARB (0.66) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL27660939 | 0.82 | RARA (0.52) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL9078617 | 0.82 | RARA (0.64) | RARBRARGRARAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5942531-A | Phenolic/naphtholic retinoids for promoting skin/exoskeleton pigmentation | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (FR) | 1999-08-24 | — | — | US | claimed |
| WO-2008126104-A2 | NOVEL PROCESS FOR PREPARATION OF ADAPALENE | INDOCO REMEDIES LIMITED (IN) | 2008-10-23 | — | — | WO | disclosed |
| EP-0920312-A4 | APOPTOSIS INDUCING ADAMANTYL DERIVATIVES AND THEIR USAGE AS ANTI-CANCER AGENTS | GALDERMA RES & DEV (FR) | 2000-11-02 | — | — | EP | disclosed |
| US-5942531-A | Phenolic/naphtholic retinoids for promoting skin/exoskeleton pigmentation | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (FR) | 1999-08-24 | — | — | US | disclosed |
| US-5939083-A | APPLYING TO SKIN, HAIR; DEFORMABLE, HOLLOW POLYMER PARTICLES | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1999-08-17 | — | — | US | disclosed |
| US-5939082-A | REGULATING MAMMALIAN SKIN PORE SIZE BY APPLYING TO THE SKIN NIACINAMIDE AND/OR TOCOPHEROL NICOTINATE | THE PROCTER & GAMBLE COMPANY (US) | 1999-08-17 | — | — | US | disclosed |
| EP-0920312-A1 | APOPTOSIS INDUCING ADAMANTYL DERIVATIVES AND THEIR USAGE AS ANTI-CANCER AGENTS | Galderma Research & Development (FR) | 1999-06-09 | — | — | EP | disclosed |
| WO-1998001132-A1 | APOPTOSIS INDUCING ADAMANTYL DERIVATIVES AND THEIR USAGE AS ANTI-CANCER AGENTS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1998-01-15 | — | — | WO | disclosed |