Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 6/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CNR2 | P34972 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | SNCA | P37840 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9056108 | 0.83 | LMNA (0.55) | ALDH1A1LMNAHTTMAPTPLA2G2A | |
| SCHEMBL8802855 | 0.81 | LMNA (0.64) | ALDH1A1LMNAMAPT | |
| SCHEMBL27522647 | 0.78 | MAPT (0.52) | ALDH1A1SMN1; SMN2LMNATDP1HTT | |
| SCHEMBL8389104 | 0.78 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2LMNATDP1HTT | |
| SCHEMBL17829679 | 0.77 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2LMNATDP1HTT | |
| SCHEMBL27503821 | 0.77 | LTB4R (0.53) | — | |
| SCHEMBL1082596 | 0.76 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2LMNATDP1HTT | |
| SCHEMBL9584018 | 0.76 | PLA2G2A (0.61) | ALDH1A1LMNAPLA2G2AMTNR1AMTNR1B | |
| SCHEMBL29377589 | 0.75 | ALDH1A1 (0.78) | ALDH1A1SMN1; SMN2LMNATDP1HTT | |
| SCHEMBL1418988 | 0.75 | ALDH1A1 (0.78) | ALDH1A1SMN1; SMN2LMNATDP1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1166169-A | Heterocyclic compounds, useful as allosteric effectors at muscarinic receptors | SANKYO CO (JP) | 1997-11-26 | — | — | CN | disclosed |
| EP-0804416-A1 | HETEROCYCLIC COMPOUNDS, USEFUL AS ALLOSTERIC EFFECTORS AT MUSCARINIC RECEPTORS | SANKYO COMPANY LIMITED (JP) | 1997-11-05 | — | — | EP | disclosed |
| WO-1996003377-A1 | HETEROCYCLIC COMPOUNDS, USEFUL AS ALLOSTERIC EFFECTORS AT MUSCARINIC RECEPTORS | SANKYO COMPANY, LIMITED (JP) | 1996-02-08 | — | — | WO | disclosed |