Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | INSR | P06213 | 2/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | CHAT | P28329 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10489995 | 0.74 | NFE2L2 (0.43) | CYP19A1MAOAMAOBBCL2BCL2L1 | |
| SCHEMBL28667698 | 0.73 | NFE2L2 (0.48) | CYP19A1MAOAMAOBBCL2BCL2L1 | |
| SCHEMBL5709420 | 0.73 | CYP19A1 (0.41) | CYP19A1MAOAMAOBTRPA1NFE2L2 | |
| SCHEMBL11312078 | 0.70 | MAOB (0.48) | CYP19A1MAOAMAOBTRPA1NFE2L2 | |
| SCHEMBL3970500 | 0.69 | BCL2 (0.41) | BCL2BCL2L1HTR2A | |
| SCHEMBL9458270 | 0.68 | BCL2 (0.37) | BCL2BCL2L1ALDH1A1HTR2A | |
| SCHEMBL11228892 | 0.68 | HRH1 (0.39) | MAOBBCL2BCL2L1CYP1A2HPGD | |
| SCHEMBL28808528 | 0.67 | TRPA1 (0.50) | BCL2BCL2L1TRPA1NFE2L2 | |
| SCHEMBL7934458 | 0.67 | TRPA1 (0.46) | CYP19A1BCL2BCL2L1TRPA1CYP1A1 | |
| SCHEMBL9806311 | 0.66 | CALM1 (0.60) | CYP19A1MAOAMAOBTRPA1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100467440-C | Quaternary bis-ammonium salt precursors and their uses as prodrugs having an antiparasitic activity | CENTRE NAT RECH SCIENT (FR) | 2009-03-11 | — | — | CN | claimed |
| CN-1733699-A | Quaternary bis-ammonium salt precursors and their uses as prodrugs having an antiparasitic activity | CENTRE NAT RECH SCIENT (FR) | 2006-02-15 | — | — | CN | claimed |
| CN-1181043-C | Bis-quaternary ammonium salt precursors and their use as antiparasitic prodrugs | ���ҿ�ѧ�о����� | 2004-12-22 | — | — | CN | claimed |
| CN-1372539-A | Bis-quaternary ammonium salt precursors and their use as antiparasitic prodrugs | CT NAT DE LA RECH SCIENT C N P (FR) | 2002-10-02 | — | — | CN | claimed |
| CN-101980706-B | Combination of salts of Chinese pulsatilla thiazolicola or precursors thereof and artemisinin or derivatives thereof for the treatment of acute malaria | SANOFI AVENTIS | 2013-11-27 | — | — | CN | disclosed |
| CN-101980706-A | Combination of a dithiazole salt or precursor thereof and artemisinin or a derivative thereof for the treatment of acute malaria | SANOFI AVENTIS | 2011-02-23 | — | — | CN | disclosed |
| CN-100467440-C | Quaternary bis-ammonium salt precursors and their uses as prodrugs having an antiparasitic activity | CENTRE NAT RECH SCIENT (FR) | 2009-03-11 | — | — | CN | disclosed |
| CN-1733699-A | Quaternary bis-ammonium salt precursors and their uses as prodrugs having an antiparasitic activity | CENTRE NAT RECH SCIENT (FR) | 2006-02-15 | — | — | CN | disclosed |
| CN-1181043-C | Bis-quaternary ammonium salt precursors and their use as antiparasitic prodrugs | ���ҿ�ѧ�о����� | 2004-12-22 | — | — | CN | disclosed |
| CN-1372539-A | Bis-quaternary ammonium salt precursors and their use as antiparasitic prodrugs | CT NAT DE LA RECH SCIENT C N P (FR) | 2002-10-02 | — | — | CN | disclosed |