Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | POLB | P06746 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3518551 | 0.71 | MAPK1 (0.53) | MEN1KMT2APOLBALDH1A1KDM4E | |
| SCHEMBL27524002 | 0.70 | ALOX15 (0.58) | MEN1KMT2APOLBALDH1A1KDM4E | |
| SCHEMBL3525569 | 0.70 | L3MBTL1 (0.68) | MEN1KMT2APOLBALDH1A1KDM4E | |
| SCHEMBL3518000 | 0.70 | KMT2A (0.66) | MEN1KMT2APOLBALDH1A1GAA | |
| SCHEMBL21679535 | 0.69 | POLB (0.56) | MEN1KMT2APOLBALDH1A1KDM4E | |
| SCHEMBL27522906 | 0.69 | KDM4E (0.45) | MEN1KMT2APOLBALDH1A1KDM4E | |
| SCHEMBL9671860 | 0.68 | ALDH1A1 (0.50) | MEN1KMT2AALDH1A1KDM4ELMNA | |
| SCHEMBL7110207 | 0.68 | PPARG (0.52) | MEN1KMT2APOLBALDH1A1KDM4E | |
| SCHEMBL7108896 | 0.67 | PPARG (0.51) | MEN1KMT2AKDM4EHDAC1HDAC2 | |
| SCHEMBL20850165 | 0.66 | MAPT (0.53) | MEN1KMT2AKDM4ELMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1279044-C | Non-steroidal progesterone receptor modulators | AKZO NOBEL NV (NL) | 2006-10-11 | — | — | CN | disclosed |
| CN-1649879-A | Non-steroidal progesterone receptor modulators | AKZO NOBEL NV (NL) | 2005-08-03 | — | — | CN | disclosed |