Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | BLM | P54132 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.53 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.47 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.47 |
| ▸ | ITGAL | P20701 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7716422 | 0.80 | L3MBTL1 (0.71) | L3MBTL1MAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL3518551 | 0.79 | MAPK1 (0.53) | L3MBTL1MAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL11704633 | 0.78 | L3MBTL1 (0.67) | L3MBTL1MAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL3518000 | 0.76 | KMT2A (0.66) | L3MBTL1MAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL27524002 | 0.76 | ALOX15 (0.58) | L3MBTL1MAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL11848833 | 0.70 | ALDH1A1 (1.00) | L3MBTL1MAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL27522906 | 0.70 | KDM4E (0.45) | L3MBTL1MAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL27522907 | 0.70 | MEN1 (0.43) | MAPK1ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL16676218 | 0.70 | L3MBTL1 (0.56) | L3MBTL1MAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL27999927 | 0.70 | L3MBTL1 (0.56) | L3MBTL1MAPK1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7737136-B2 | Non-steroidal progesterone receptor modulators | N.V. ORGANON (NL) | 2010-06-15 | — | — | US | disclosed |
| EP-1495030-B1 | NON-STEROIDAL PROGESTERONE RECEPTOR MODULATORS | ORGANON NV (NL) | 2008-08-13 | — | — | EP | disclosed |
| US-20050171087-A1 | Non-steroidal progesterone receptor modulators | MERCK SHARP & DOHME B.V. (NL) | 2005-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171087-A1 | Non-steroidal progesterone receptor modulators | PGR, PGRMC1, PGRMC2 | L3MBTL1 4849/4885MAPK1 971/4885ALDH1A1 1163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.