Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 8/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.37 |
| ▸ | GUSB | P08236 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27509165 | 0.92 | MPO (0.41) | TDO2IDO1MAPTALDH1A1MEN1 | |
| SCHEMBL27510230 | 0.89 | THRB (0.40) | TDO2IDO1MAPTALDH1A1RORC | |
| SCHEMBL27493350 | 0.83 | RORC (0.41) | MAPTALDH1A1RORCGUSB | |
| SCHEMBL27495316 | 0.83 | TDO2 (0.42) | TDO2MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL27524772 | 0.79 | GPR84 (0.42) | TDO2MEN1KMT2ANR3C1 | |
| SCHEMBL27511350 | 0.76 | TDO2 (0.37) | TDO2MAPTNR3C1GUSBSMN1; SMN2 | |
| SCHEMBL27510617 | 0.76 | HASPIN (0.46) | MAPTALDH1A1MEN1KMT2ARORC | |
| SCHEMBL27495706 | 0.75 | LMNA (0.42) | MAPTALDH1A1GUSBLMNASMN1; SMN2 | |
| SCHEMBL28741350 | 0.71 | ALDH1A1 (0.37) | TDO2ALDH1A1KMT2ANR3C1LMNA | |
| SCHEMBL27563843 | 0.70 | SMN1; SMN2 (0.50) | MAPTALDH1A1MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1223650-A | Piperidines and pyrrolidines | MERCK PATENT GMBH (DE) | 1999-07-21 | — | — | CN | disclosed |