Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MIF | P14174 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20645838 | 0.83 | MIF (0.50) | HTTMIFCYP1A2CYP2C19NPSR1 | |
| SCHEMBL20645845 | 0.80 | MIF (0.48) | HTTMIFCYP1A2CYP2C19NPC1 | |
| SCHEMBL8494420 | 0.77 | F10 (0.46) | HTTMIFNPC1RAB9APOLB | |
| SCHEMBL20640544 | 0.76 | MIF (0.50) | HTTMIFCYP1A2CYP2C19NPC1 | |
| SCHEMBL27550992 | 0.76 | MIF (0.47) | HTTMIFCYP1A2CYP2C19NPSR1 | |
| SCHEMBL10757347 | 0.75 | MIF (0.46) | HTTMIFTSHRTDP1L3MBTL1 | |
| SCHEMBL8444142 | 0.71 | MIF (0.58) | HTTMIFCYP1A2CYP2C19POLB | |
| SCHEMBL10758499 | 0.70 | MIF (0.42) | HTTMIFCYP1A2CYP2C19CYP2D6 | |
| SCHEMBL20640947 | 0.70 | MIF (0.50) | HTTMIFCYP1A2CYP2C19NPSR1 | |
| SCHEMBL12461232 | 0.69 | CYP4F2 (0.37) | HTTMIFHPGDCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1285352-A | Preparation for lignal like material | SHIONOGI & CO (JP) | 2001-02-28 | — | — | CN | disclosed |