Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 3/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 8/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8331089 | 0.91 | ELANE (0.39) | ACKR3HDAC6ELANEHCRTR1HCRTR2 | |
| SCHEMBL8329113 | 0.77 | RBP4 (0.44) | HCRTR1CNR2DHODHHSD17B10KDM4E | |
| SCHEMBL27764496 | 0.71 | HDAC6 (0.50) | HDAC6ELANEHCRTR1HCRTR2CNR2 | |
| Benzyl Alcohol SCHEMBL27535788 | 0.70 | CYP3A4 (0.38) | HSD17B10P2RX7KDM4E | |
| SCHEMBL8438955 | 0.67 | P2RX7 (0.46) | P2RX7 | |
| SCHEMBL27528135 | 0.66 | RPS6KB1 (0.33) | — | |
| SCHEMBL1014875 | 0.65 | DHODH (0.38) | DHODHHTTKDM4E | |
| SCHEMBL29488337 | 0.64 | NAPRT (0.58) | HDAC6HCRTR1HCRTR2DHODHHTT | |
| SCHEMBL413572 | 0.64 | NAPRT (0.58) | HDAC6HCRTR1HCRTR2DHODHHTT | |
| SCHEMBL23012187 | 0.63 | KDM4E (0.55) | DHODHKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1230943-A | Process for the preparation of aryl-beta-diketones, aryl-pyrimidinones and crop protection intermediates | ZENECA LTD (GB) | 1999-10-06 | — | — | CN | disclosed |