Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 13/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | PAK1 | Q13153 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8329113 | 0.75 | RBP4 (0.44) | TSHR | |
| SCHEMBL8331089 | 0.73 | ELANE (0.39) | — | |
| SCHEMBL7032023 | 0.72 | TSHR (0.71) | P2RX7TSHRJAK2L3MBTL1TAS1R3 | |
| SCHEMBL9113731 | 0.72 | P2RX7 (0.47) | P2RX7TSHRALOX12L3MBTL1TAS1R3 | |
| SCHEMBL1014875 | 0.72 | DHODH (0.38) | L3MBTL1 | |
| SCHEMBL3823060 | 0.70 | PARP1 (0.38) | — | |
| SCHEMBL9134364 | 0.69 | TSHR (0.65) | P2RX7TSHRJAK2L3MBTL1TAS1R3 | |
| SCHEMBL8606571 | 0.68 | TSHR (0.63) | P2RX7TSHRJAK2L3MBTL1TAS1R3 | |
| SCHEMBL1015210 | 0.67 | KDM4E (0.38) | TSHRL3MBTL1 | |
| SCHEMBL534385 | 0.63 | P2RX7 (1.00) | P2RX7TSHRJAK2PAK1TAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0939756-A2 | A PROCESS FOR THE STEREOSELECTIVE REDUCTION OF ALPHA,BETA-UNSATURATED KETONES | CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) | 1999-09-08 | — | — | EP | disclosed |
| EP-0929510-A2 | PROCESSES FOR THE PREPARATION OF ARYL-$g(b)-DIKETONES, ARYL-PYRIMIDINE KETONES AND CROP PROTECTION INTERMEDIATES | ZENECA LIMITED (GB) | 1999-07-21 | — | — | EP | disclosed |
| US-5925795-A | Processes for the preparation of aryl-β-diketones, arylpyrimidine ketones and crop protection intermediates | ZENECA LIMITED (GB) | 1999-07-20 | — | — | US | disclosed |
| WO-1998011046-A2 | PROCESSES FOR THE PREPARATION OF ARYL-β-DIKETONES, ARYL-PYRIMIDINE KETONES AND CROP PROTECTION INTERMEDIATES | ZENECA LIMITED (GB) | 1998-03-19 | — | — | WO | disclosed |
| WO-1997022602-A2 | A PROCESS FOR THE STEREOSELECTIVE REDUCTION OF α,β-UNSATURATED KETONES | CHINOIN, Gyógyszer és Vegyészeti (HU) | 1997-06-26 | — | — | WO | disclosed |