Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | CA7 | P43166 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | NOS3 | P29474 | 2/20 | 0.47 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.47 |
| ▸ | HTR3B | O95264 | 1/20 | 0.47 |
| ▸ | HTR3A | P46098 | 1/20 | 0.47 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.47 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL28711563 | 0.96 | LTA4H (0.50) | CA1CA2CA7CA9CA12 | |
| SCHEMBL27896820 | 0.75 | HTR3E (0.53) | CA1CA2CA7CA9NOS3 | |
| SCHEMBL29446760 | 0.74 | ALDH1A1 (0.58) | TSHRSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL156005 | 0.73 | CA1 (0.58) | CA1CA2CA7CA9CA12 | |
| SCHEMBL1900456 | 0.72 | CA1 (0.65) | CA1CA2CA7CA9CA12 | |
| SCHEMBL1405603 | 0.72 | CA1 (0.65) | CA1CA2CA7CA9CA12 | |
| SCHEMBL1405602 | 0.72 | CA1 (0.65) | CA1CA2CA7CA9CA12 | |
| Ammonia Solution, Strong SCHEMBL28131657 | 0.71 | TDP1 (0.40) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL28031495 | 0.71 | TDP1 (0.40) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| Hydrochloric Acid SCHEMBL27570550 | 0.71 | TDP1 (0.40) | NOS3HTR3EHTR3BHTR3AHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116239547-A | Synthesis method of benzo [ i ] [1,2] thiazine-3, 7, 8-trione-1-oxygen series compound | 浙大城市学院 | 2023-06-09 | — | — | CN | disclosed |
| CN-110143999-A | Have cytotoxicity and antimitotic compound and its application method | 酵活有限公司 | 2019-08-20 | — | — | CN | disclosed |
| CN-105358174-B | Cytotoxic and antimitotic compounds and methods of use thereof | 酵活有限公司 | 2019-03-15 | — | — | CN | disclosed |
| CN-104507481-B | 7-oxo-4, 7-dihydro-pyrazolo [1,5-a ] pyrimidine derivatives for the treatment, amelioration or prevention of a viral disease | 萨维拉制药有限公司 | 2017-08-04 | — | — | CN | disclosed |
| CN-104334563-B | 7-oxo-thiazolopyridine carbonic acid derivatives and their use in the treatment, amelioration or prevention of viral diseases | 萨维拉制药有限公司 | 2017-03-08 | — | — | CN | disclosed |
| CN-106459162-A | VAR2CSA-drug conjugates | 酵活有限公司 | 2017-02-22 | — | — | CN | disclosed |
| CN-103781813-B | The epoxy resin adduct mixed | 蓝立方知识产权有限责任公司 | 2016-09-14 | — | — | CN | disclosed |
| CN-103228694-B | Heat curable composition and the thermosetting material prepared by heat curable composition | Blue Cube Intellectual Property Co.,Ltd. (US) | 2016-04-27 | — | — | CN | disclosed |
| CN-105358174-A | Cytotoxic and antimitotic compounds and methods of use thereof | CT FOR DRUG RES AND DEV | 2016-02-24 | — | — | CN | disclosed |
| CN-104507481-A | 7-oxo-4, 7-dihydro-pyrazolo [1,5-a ] pyrimidine derivatives for the treatment, amelioration or prevention of a viral disease | SAVIRA PHARMACEUTICALS GMBH | 2015-04-08 | — | — | CN | disclosed |
| CN-104334563-A | 7-oxo-thiazolopyridine carbonic acid derivatives and their use in the treatment, amelioration or prevention of viral diseases | SAVIRA PHARMACEUTICALS GMBH | 2015-02-04 | — | — | CN | disclosed |
| CN-1240429-A | Preparation and use of ortho-sulfonamido aryl hydroxamic acids as matrix metalloproteinase and TACE inhibitors | AMERICAN CYANAMID CO (US) | 2000-01-05 | — | — | CN | disclosed |