Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | CES1 | P23141 | 2/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | F2R | P25116 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27383222 | 0.88 | FFAR3 (0.42) | SMN1; SMN2L3MBTL1HPGDKMT2AF2 | |
| SCHEMBL6627600 | 0.86 | CES1 (0.39) | SMN1; SMN2L3MBTL1HPGDKMT2AF2 | |
| Pyridine SCHEMBL27857276 | 0.78 | KMT2A (0.37) | SMN1; SMN2L3MBTL1HPGDKMT2AF2 | |
| Biphenyl SCHEMBL460021 | 0.76 | SMN1; SMN2 (0.64) | SMN1; SMN2L3MBTL1HPGDMAPTCES1 | |
| Biphenyl SCHEMBL27530949 | 0.75 | NAAA (0.67) | SMN1; SMN2L3MBTL1HPGDKMT2AMAPT | |
| Biphenyl SCHEMBL27630230 | 0.74 | NAAA (0.65) | SMN1; SMN2L3MBTL1HPGDKMT2AALDH1A1 | |
| Biphenyl SCHEMBL27556919 | 0.72 | TSHR (0.61) | SMN1; SMN2L3MBTL1HPGDMAPTCES1 | |
| SCHEMBL18787369 | 0.72 | FBP1 (0.33) | — | |
| SCHEMBL3733726 | 0.69 | SMN1; SMN2 (1.00) | SMN1; SMN2L3MBTL1HPGDMAPTALDH1A1 | |
| Biphenyl SCHEMBL28325885 | 0.69 | SMN1; SMN2 (0.56) | SMN1; SMN2L3MBTL1HPGDKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1304929-A | 4-hydroxy-4-phenyl piperidine derivative and medicine containing said derivative | SS PHARMACEUTICAL CO (JP) | 2001-07-25 | — | — | CN | disclosed |