SCHEMBL27531134

SCHEMBL27531134

Nc1cc2nc3c[c]ccc3nc2cc1Cl

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.42
POLB P06746 3/20 0.42
MAPT P10636 3/20 0.42
KMT2A Q03164 3/20 0.42
NPC1 O15118 2/20 0.42
USP2 O75604 1/20 0.42
CACNA1B Q00975 1/20 0.42
APBA1 Q02410 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
CASP6 P55212 2/20 0.41
PGK1 P00558 1/20 0.40
ALDH1A1 P00352 3/20 0.39
KDM4E B2RXH2 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
LMNA P02545 1/20 0.39
BLM P54132 1/20 0.39
CASP9 P55211 1/20 0.39
CASP8 Q14790 1/20 0.39
GAA P10253 2/20 0.37
PKM P14618 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27391068 0.79 APAF1 (0.53) MEN1POLBMAPTKMT2ANPC1
SCHEMBL8719387 0.77 KMT2A (0.47) MEN1POLBMAPTKMT2ANPC1
SCHEMBL27514406 0.74 KMT2A (0.48) MEN1POLBMAPTKMT2ANPC1
SCHEMBL11227486 0.73 TDP1 (0.50) L3MBTL1KDM4EPKMTDP1
SCHEMBL23844 0.71 MAPT (0.55) MEN1POLBMAPTKMT2ANPC1
SCHEMBL9739674 0.71 GAA (0.42) NPC1CASP6ALDH1A1GAATSHR
SCHEMBL20475600 0.68 NQO1 (0.33) MAPTCASP6ALDH1A1KDM4EGAA
SCHEMBL6108034 0.67 GAA (0.48) MEN1POLBMAPTKMT2ANPC1
SCHEMBL6714495 0.65
SCHEMBL194246 0.65 MAPT (0.39) MEN1MAPTKMT2ANPC1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1084357-C Dyeing composition comprising a myceliophthora laccase, use thereof for dyeing keratin fibres and method for dyeing keratin fibres NOVO TJMEIDS AS (DK) 2002-05-08 CN claimed
CN-1203615-A Laccases with improved dyeing properties NOVO NORDISK AS (DK) 1998-12-30 CN claimed
CN-1167791-C Storage stable liquid formulation comprising a laccase ŵ����÷�����޹�˾ 2004-09-22 CN disclosed
CN-1084357-C Dyeing composition comprising a myceliophthora laccase, use thereof for dyeing keratin fibres and method for dyeing keratin fibres NOVO TJMEIDS AS (DK) 2002-05-08 CN disclosed
CN-1250475-A Storage stable liquid formulation comprising a laccase NOVO NORDISK AS (DK) 2000-04-12 CN disclosed
CN-1203615-A Laccases with improved dyeing properties NOVO NORDISK AS (DK) 1998-12-30 CN disclosed