Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 7/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 6/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.37 |
| ▸ | GABRD | O14764 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.37 |
| ▸ | GABRE | P78334 | 1/20 | 0.37 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.37 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.37 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.37 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27565351 | 0.86 | POLB (0.41) | HCAR2XDHSLC22A12CYP2A6HTT | |
| SCHEMBL27568453 | 0.83 | ERN1 (0.42) | HCAR2XDHSLC22A12GABRPGABRD | |
| SCHEMBL27585151 | 0.79 | HTT (0.50) | HCAR2CYP2A6KDM4ELMNAHTT | |
| SCHEMBL27341172 | 0.78 | MEN1 (0.40) | KDM4EMCL1KDM4CSMN1; SMN2ALDH1A1 | |
| SCHEMBL10789318 | 0.76 | FABP4 (0.47) | LDHAMCL1ALDH1A1 | |
| SCHEMBL27565330 | 0.75 | SORT1 (0.42) | XDHSLC22A12GABRPGABRDGABRA1 | |
| SCHEMBL28796441 | 0.73 | KMT2A (0.36) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL27747520 | 0.73 | MCL1 (0.44) | KDM4ELMNAMCL1ALDH1A1 | |
| SCHEMBL27287018 | 0.73 | ACMSD (0.47) | LDHAMCL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL28750800 | 0.72 | NPC1 (0.46) | CYP2A6KDM4ELMNAMCL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1392874-A | Cyclic amidine compounds | SUNTORY LTD (JP) | 2003-01-22 | — | — | CN | claimed |
| CN-1252069-C | 2-aryl-naphthyridin-4-ones as antitumor agents | UNIV NORTH CAROLINA CHAPEL HILL (US) | 2006-04-19 | — | — | CN | disclosed |
| CN-1392874-A | Cyclic amidine compounds | SUNTORY LTD (JP) | 2003-01-22 | — | — | CN | disclosed |
| CN-1259947-A | 2-aryl-naphthyridin-4-ones as antitumor agents | UNIV NORTH CAROLINA CHAPEL HILL (US) | 2000-07-12 | — | — | CN | disclosed |