Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MKNK1 | Q9BUB5 | 5/20 | 0.49 |
| ▸ | MKNK2 | Q9HBH9 | 5/20 | 0.49 |
| ▸ | KMO | O15229 | 2/20 | 0.44 |
| ▸ | DHODH | Q02127 | 4/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27568453 | 0.83 | ERN1 (0.42) | HTTKDM4ELMNAALDH1A1HCAR2 | |
| SCHEMBL10789318 | 0.82 | FABP4 (0.47) | CYP3A4CYP2C9ALDH1A1 | |
| SCHEMBL27341172 | 0.81 | MEN1 (0.40) | KDM4EDHODHALDH1A1L3MBTL1 | |
| SCHEMBL27565330 | 0.81 | SORT1 (0.42) | KDM4ELMNAALDH1A1 | |
| SCHEMBL27287018 | 0.80 | ACMSD (0.47) | DHODHALDH1A1 | |
| SCHEMBL27532005 | 0.79 | HCAR2 (0.44) | HTTKDM4ELMNACYP2A6ALDH1A1 | |
| SCHEMBL28404845 | 0.79 | KMO (0.57) | HTTKDM4ELMNAMKNK1MKNK2 | |
| SCHEMBL27468806 | 0.78 | GPR35 (0.49) | HTTKDM4ELMNAMKNK1MKNK2 | |
| SCHEMBL27565351 | 0.77 | POLB (0.41) | HTTCYP2A6ALDH1A1HCAR2 | |
| SCHEMBL27864736 | 0.77 | DHODH (0.41) | HTTKDM4ELMNADHODHCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1392874-A | Cyclic amidine compounds | SUNTORY LTD (JP) | 2003-01-22 | — | — | CN | claimed |