Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.56 |
| ▸ | TEAD3 | Q99594 | 2/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.49 |
| ▸ | GBA1 | P04062 | 2/20 | 0.48 |
| ▸ | UGCG | Q16739 | 2/20 | 0.48 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.47 |
| ▸ | NPY1R | P25929 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7389601 | 1.00 | LTA4H (0.56) | LTA4HTEAD3HRH3GBA1UGCG | |
| SCHEMBL7387110 | 0.98 | LTA4H (0.57) | LTA4HTEAD3HRH3GBA1UGCG | |
| SCHEMBL7395255 | 0.94 | TEAD3 (0.59) | LTA4HTEAD3HRH3KDM4EALDH1A1 | |
| SCHEMBL7388780 | 0.91 | LTA4H (0.67) | LTA4HTEAD3HRH3KDM4EALDH1A1 | |
| SCHEMBL7394897 | 0.87 | HRH3 (0.58) | HRH3SIGMAR1MEN1KMT2A | |
| SCHEMBL27533341 | 0.86 | LTA4H (0.70) | LTA4HTEAD3HRH3KDM4EALDH1A1 | |
| SCHEMBL7389363 | 0.85 | HRH3 (0.51) | HRH3GBA1UGCGGBA2SIGMAR1 | |
| SCHEMBL27540109 | 0.84 | LTA4H (0.72) | LTA4HTEAD3HRH3KDM4EALDH1A1 | |
| SCHEMBL7391532 | 0.84 | GBA1 (0.54) | LTA4HHRH3GBA1UGCGGBA2 | |
| SCHEMBL6947688 | 0.82 | LTA4H (0.54) | LTA4HTEAD3HRH3GBA1UGCG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5864039-A | THERAPEUTIC TREATMENT OF VARIOUS GASTROINTESTINAL DISEASES, CENTRAL NERVOUS DISORDERS, CARDIOVASCULAR DISORDERS, URINARY DISEASES, UROGENITAL DISORDERS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1999-01-26 | — | — | US | disclosed |
| EP-0873990-A1 | BENZOIC ACID COMPOUNDS AND MEDICINAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-10-28 | — | — | EP | disclosed |