Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 6/20 | 0.45 |
| ▸ | MMP1 | P03956 | 6/20 | 0.45 |
| ▸ | MMP13 | P45452 | 6/20 | 0.45 |
| ▸ | MMP9 | P14780 | 5/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | BMP1 | P13497 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | STAT3 | P40763 | 2/20 | 0.42 |
| ▸ | TAS2R14 | Q9NYV8 | 3/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7317819 | 0.78 | MMP9 (0.58) | ADAM17MMP1MMP13MMP9KDM4E | |
| SCHEMBL27569107 | 0.75 | KEAP1 (0.51) | ADAM17MMP1MMP13MMP9MMP2 | |
| SCHEMBL27511381 | 0.73 | MMP9 (0.69) | ADAM17MMP1MMP13MMP9 | |
| SCHEMBL7317816 | 0.72 | POLB (0.41) | ADAM17MMP1MMP13MMP9MMP2 | |
| SCHEMBL7311189 | 0.71 | MMP9 (0.57) | ADAM17MMP1MMP13MMP9KEAP1 | |
| SCHEMBL7315684 | 0.71 | MMP9 (0.57) | ADAM17MMP1MMP13MMP9BMP1 | |
| SCHEMBL27529783 | 0.71 | MMP9 (0.62) | ADAM17MMP1MMP13MMP9MMP2 | |
| SCHEMBL7323912 | 0.69 | MMP9 (0.65) | ADAM17MMP1MMP13MMP9 | |
| SCHEMBL7318672 | 0.68 | MMP13 (0.71) | ADAM17MMP1MMP13MMP9ALDH1A1 | |
| SCHEMBL4012164 | 0.67 | TAS2R14 (0.53) | KDM4EALDH1A1TAS2R14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1240429-A | Preparation and use of ortho-sulfonamido aryl hydroxamic acids as matrix metalloproteinase and TACE inhibitors | AMERICAN CYANAMID CO (US) | 2000-01-05 | — | — | CN | disclosed |