Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3936988 | 0.91 | LMNA (0.54) | ALDH1A1LMNAACEHSD17B10KDM4E | |
| SCHEMBL14542192 | 0.89 | GAA (0.48) | ALDH1A1LMNAACEHSD17B10KMT2A | |
| SCHEMBL14542443 | 0.85 | ACE (0.48) | ACEKMT2A | |
| SCHEMBL13879233 | 0.82 | ALDH1A1 (0.37) | ALDH1A1HSD17B10MEN1KMT2AOPRK1 | |
| SCHEMBL13879329 | 0.81 | DPP4 (0.40) | ALDH1A1KMT2AGAA | |
| SCHEMBL27559390 | 0.77 | SLC7A5 (0.50) | ALDH1A1LMNAHSD17B10KDM4EMEN1 | |
| SCHEMBL3936455 | 0.76 | ACE (0.54) | ALDH1A1ACEHSD17B10KMT2A | |
| SCHEMBL5151943 | 0.76 | ACE (0.54) | ALDH1A1ACEHSD17B10KMT2A | |
| SCHEMBL3936484 | 0.76 | ACE (0.54) | ALDH1A1ACEHSD17B10KMT2A | |
| SCHEMBL3936490 | 0.76 | ACE (0.54) | ALDH1A1ACEHSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007038116-A1 | PROCESS TO PREPARE AMINO ACID DERIVATIVES | DOW GLOBAL TECHNOLOGIES INC. (US) | 2007-04-05 | — | — | WO | disclosed |