Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 14/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 14/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 12/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27681390 | 0.82 | SLC6A2 (0.41) | HTR2ASLC6A2SLC6A3SLC6A4OPRM1 | |
| SCHEMBL10880376 | 0.81 | OPRM1 (0.37) | HTR2ASLC6A2SLC6A3SLC6A4OPRM1 | |
| SCHEMBL13728947 | 0.77 | SLC6A2 (0.36) | HTR2ASLC6A2SLC6A3SLC6A4 | |
| SCHEMBL13728952 | 0.75 | HTR1A (0.41) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL1334863 | 0.74 | HTR2A (0.44) | HTR2ASLC6A2SLC6A3SLC6A4OPRM1 | |
| SCHEMBL977558 | 0.73 | HTR2A (0.47) | HTR2ASLC6A2SLC6A3SLC6A4OPRM1 | |
| Bromide SCHEMBL5224748 | 0.72 | HTR2A (0.43) | HTR2ASLC6A2SLC6A3SLC6A4OPRM1 | |
| SCHEMBL31367105 | 0.72 | HTR1A (0.43) | SLC6A2SLC6A3OPRM1CHRNB2CHRNB4 | |
| SCHEMBL16743054 | 0.72 | CHRNB2 (0.36) | SLC6A2SLC6A3OPRM1CHRNB2CHRNB4 | |
| SCHEMBL7592931 | 0.72 | PTGS2 (0.42) | SLC6A2SLC6A3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1267087-C | Pharmaceutical tablet | PHARMACIA CORP (US) | 2006-08-02 | — | — | CN | disclosed |
| CN-1630512-A | Pharmaceutical tablet | PHARMACIA CORP (US) | 2005-06-22 | — | — | CN | disclosed |