Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 5/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GRM6 | O15303 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6343183 | 0.78 | MAPT (0.40) | ALDH1A1LMNATSHRTDP1KDR | |
| SCHEMBL9330417 | 0.76 | ALDH1A1 (0.40) | ALDH1A1LMNATSHRTDP1ESR1 | |
| SCHEMBL9330412 | 0.76 | ALDH1A1 (0.40) | ALDH1A1LMNATSHRTDP1ESR1 | |
| SCHEMBL23069579 | 0.73 | TSHR (0.48) | ALDH1A1LMNATSHRESR1MAPK1 | |
| SCHEMBL5653476 | 0.72 | LMNA (0.43) | ALDH1A1LMNATSHRTDP1L3MBTL1 | |
| SCHEMBL4904690 | 0.70 | TDP1 (0.43) | ALDH1A1LMNATSHRTDP1L3MBTL1 | |
| SCHEMBL2404923 | 0.70 | ALDH1A1 (0.50) | ALDH1A1LMNATSHRTDP1ESR1 | |
| SCHEMBL160192 | 0.69 | ALDH1A1 (0.44) | ALDH1A1LMNATSHRTDP1ESR1 | |
| SCHEMBL1149224 | 0.69 | TSHR (0.43) | ALDH1A1TSHRTDP1L3MBTL1SMN1; SMN2 | |
| SCHEMBL6325084 | 0.68 | LMNA (0.58) | ALDH1A1LMNATSHRESR1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1312153-C | Pyrrolopyrimidinone derivatives, process for their preparation and their use | SK CHEMICALS CO LTD (KR) | 2007-04-25 | — | — | CN | disclosed |
| CN-1422271-A | Pyrrolopyrimidinone derivatives, process for their preparation and their use | SK CHEMICALS CO LTD (KR) | 2003-06-04 | — | — | CN | disclosed |