Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4334753 | 0.86 | TDP1 (0.46) | TDP1POLBL3MBTL1APEX1HDAC4 | |
| SCHEMBL5653476 | 0.84 | LMNA (0.43) | TDP1POLBL3MBTL1APEX1PARP1 | |
| SCHEMBL28151189 | 0.81 | PARP1 (0.37) | PARP1LMNAMAP3K14BCHEACHE | |
| SCHEMBL4379296 | 0.78 | POLB (0.43) | TDP1POLBL3MBTL1APEX1HDAC4 | |
| SCHEMBL6343183 | 0.76 | MAPT (0.40) | TDP1L3MBTL1LMNAMAPTTSHR | |
| SCHEMBL14398922 | 0.75 | POLB (0.41) | TDP1POLBL3MBTL1APEX1HDAC4 | |
| SCHEMBL27907517 | 0.74 | ALDH1A1 (0.43) | TDP1POLBL3MBTL1APEX1HDAC8 | |
| SCHEMBL4913277 | 0.74 | POLB (0.40) | TDP1POLBL3MBTL1APEX1HDAC4 | |
| SCHEMBL28614024 | 0.74 | POLB (0.40) | TDP1POLBL3MBTL1APEX1HDAC4 | |
| SCHEMBL6794236 | 0.74 | L3MBTL1 (0.40) | TDP1POLBL3MBTL1APEX1HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080233410-A1 | Transition metal complex compound | IDEMITSU KOSAN CO., LTD. (JP) | 2008-09-25 | — | — | US | disclosed |
| US-20070141397-A1 | TRANSITION METAL COMPLEX COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE COMPOUND | IDEMITSU KOSAN CO., LTD (JP) | 2007-06-21 | — | — | US | disclosed |
| CN-1312153-C | Pyrrolopyrimidinone derivatives, process for their preparation and their use | SK CHEMICALS CO LTD (KR) | 2007-04-25 | — | — | CN | disclosed |
| WO-2005011675-A1 | DERIVATIVES OF 3-HYDROXY-PYRROLE-2,4-DICARBOXYLIC ACID AND USES THEREOF | AVALON PHARMACEUTICALS (US) | 2005-02-10 | — | — | WO | disclosed |
| CN-1422271-A | Pyrrolopyrimidinone derivatives, process for their preparation and their use | SK CHEMICALS CO LTD (KR) | 2003-06-04 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080233410-A1 | Transition metal complex compound | EMC2, INTS9, LEF1 | TDP1 3912/4885POLB 1784/4885L3MBTL1 947/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.