Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ACP3 | P15309 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27879415 | 0.82 | FNTA (0.33) | SMN1; SMN2 | |
| SCHEMBL28066341 | 0.74 | — | — | |
| SCHEMBL28522028 | 0.74 | — | — | |
| SCHEMBL28512202 | 0.74 | — | — | |
| SCHEMBL28522026 | 0.74 | TDP2 (0.31) | — | |
| SCHEMBL28650388 | 0.73 | SETD7 (0.31) | — | |
| SCHEMBL28897961 | 0.70 | CES1 (0.31) | — | |
| SCHEMBL20553971 | 0.67 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL19834896 | 0.65 | ALDH1A1 (0.35) | ALDH1A1 | |
| Biphenyl SCHEMBL342228 | 0.65 | ALDH1A1 (0.60) | ACP3NPC1ALDH1A1RAB9APTPN5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101198652-B | Polycarbonate resin composition and molded article | MITSUBISHI ENG PLASTICS CORP | 2012-07-04 | — | — | CN | disclosed |
| CN-100584907-C | Cured resin composition | SUMITOMO CHEMICAL CO | 2010-01-27 | — | — | CN | disclosed |
| CN-100475902-C | Curable resin composition | SUMITOMO CHEMICAL CO (JP) | 2009-04-08 | — | — | CN | disclosed |
| CN-101274994-A | Stabilizing agent compound for koroseal | ADEKA CORP (JP) | 2008-10-01 | — | — | CN | disclosed |
| CN-100406488-C | Polyisocyanate solution, and adhesive and coating using the same | NIPPON POLYURETHANE KOGYO KK (JP) | 2008-07-30 | — | — | CN | disclosed |
| CN-101081956-A | Cured resin composition | SUMITOMO CHEMICAL CO (JP) | 2007-12-05 | — | — | CN | disclosed |
| CN-1280381-C | Oil-keeping treating agent, oil-keeping treating method and treated colck and watch by the same method | CITIZEN WATCH CO LTD (JP) | 2006-10-18 | — | — | CN | disclosed |
| CN-1569954-A | Curable resin composition | SUMITOMO CHEMICAL CO (JP) | 2005-01-26 | — | — | CN | disclosed |
| CN-1504490-A | Polyisocyanate solution, and adhesive and coating using the same | 日本聚氨酯工业株式会社 | 2004-06-16 | — | — | CN | disclosed |
| CN-1487051-A | Oil-keeping treating agent, oil-keeping treating method and treated colck and watch by the same method | 西铁城时计株式会社 | 2004-04-07 | — | — | CN | disclosed |