SCHEMBL27547199

SCHEMBL27547199

CC(C)(C)OC(=O)c1sc(Cl)cc1N

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.42
KDM4E B2RXH2 6/20 0.42
NPC1 O15118 6/20 0.42
RAB9A P51151 6/20 0.42
CASP3 P42574 2/20 0.42
SENP8 Q96LD8 2/20 0.42
SENP7 Q9BQF6 2/20 0.42
SENP6 Q9GZR1 2/20 0.42
GRM6 O15303 1/20 0.38
CISD2 Q8N5K1 1/20 0.36
IKBKB O14920 2/20 0.36
CA12 O43570 2/20 0.36
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
CA9 Q16790 2/20 0.36
ALDH1A1 P00352 3/20 0.36
POLB P06746 1/20 0.36
MEN1 O00255 4/20 0.35
KMT2A Q03164 4/20 0.35
SMN1; SMN2 Q16637 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10566679 0.81 KDM4E (0.60) MAPTKDM4ENPC1RAB9ACASP3
Hydrochloric Acid SCHEMBL31120455 0.79 KDM4E (0.59) MAPTKDM4ENPC1RAB9ACASP3
SCHEMBL27805811 0.73 GRM6 (0.40) MAPTKDM4ENPC1RAB9ACASP3
SCHEMBL16425576 0.73 MAPT (0.56) MAPTKDM4ENPC1RAB9ACASP3
SCHEMBL28226525 0.72 DAO (0.47) MAPTKDM4ENPC1RAB9ACASP3
SCHEMBL12247521 0.72 IKBKB (0.56) MAPTKDM4ENPC1RAB9ACASP3
SCHEMBL16417070 0.72 KDM4E (0.36) MAPTKDM4ENPC1RAB9ACASP3
SCHEMBL19066913 0.71 CISD2 (0.42) MAPTKDM4ENPC1RAB9AGRM6
SCHEMBL3119240 0.70 ALOX15 (0.44) MAPTKDM4EGRM6CA12CA1
SCHEMBL16426250 0.70 IKBKB (0.55) MAPTKDM4ENPC1RAB9ACASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1322195-A Substituted pyrroldinone, thizolidinone or oxazolidinone as herbicides ZENECA LTD (GB) 2001-11-14 CN disclosed