Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 7/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27604183 | 0.79 | ATM (0.38) | ALDH1A1KDM4EGAAATMSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL27604028 | 0.78 | ATM (0.37) | ALDH1A1KDM4EGAAATMSMN1; SMN2 | |
| SCHEMBL11669167 | 0.77 | ALDH1A1 (0.71) | ALDH1A1KDM4EGAAATMSMN1; SMN2 | |
| SCHEMBL5810083 | 0.76 | ATM (0.79) | ALDH1A1KDM4EGAAATMSMN1; SMN2 | |
| SCHEMBL24619210 | 0.76 | ALDH1A1 (0.69) | ALDH1A1KDM4EGAAATMSMN1; SMN2 | |
| SCHEMBL27525064 | 0.76 | MAP4K4 (0.43) | ALDH1A1KDM4ESMN1; SMN2HPGDHSD17B10 | |
| SCHEMBL27586210 | 0.75 | KDM4E (0.38) | ALDH1A1KDM4EGAAATMSMN1; SMN2 | |
| SCHEMBL16974161 | 0.75 | ALDH1A1 (0.72) | ALDH1A1KDM4EGAAATMSMN1; SMN2 | |
| SCHEMBL5809940 | 0.74 | ALDH1A1 (1.00) | ALDH1A1KDM4EGAAATMSMN1; SMN2 | |
| SCHEMBL27721451 | 0.74 | KDM4E (0.35) | ALDH1A1KDM4EGAAATMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1274676-C | Quinoline and quinazoline derivatives | HOFFMANN LA ROCHE (CH) | 2006-09-13 | — | — | CN | disclosed |
| CN-1444563-A | Quinoline and quinazoline derivatives | HOFFMANN LA ROCHE (CH) | 2003-09-24 | — | — | CN | disclosed |