Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 2/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | IGFBP3 | P17936 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27483932 | 0.92 | CYP2C9 (0.33) | KMT2AHPGDMEN1LMNAALDH1A1 | |
| SCHEMBL27499051 | 0.88 | NFE2L2 (0.35) | CRHR1METAP2KMT2AHPGDMEN1 | |
| SCHEMBL615242 | 0.84 | LMNA (0.37) | METAP2KMT2AHPGDMEN1LMNA | |
| SCHEMBL28781833 | 0.82 | LMNA (0.36) | CRHR1METAP2KMT2AHPGDMEN1 | |
| SCHEMBL2919385 | 0.82 | LMNA (0.36) | CRHR1METAP2KMT2AHPGDMEN1 | |
| Ammonia Solution, Strong SCHEMBL2909573 | 0.82 | LMNA (0.36) | CRHR1METAP2KMT2AHPGDMEN1 | |
| SCHEMBL2909743 | 0.82 | LMNA (0.36) | CRHR1METAP2KMT2AHPGDMEN1 | |
| Benzophenone SCHEMBL28167645 | 0.80 | ALDH1A1 (0.42) | KMT2AHPGDMEN1LMNASMN1; SMN2 | |
| SCHEMBL27485651 | 0.78 | KMT2A (0.35) | CRHR1KMT2AHPGDMEN1LMNA | |
| SCHEMBL27485331 | 0.78 | CYP3A4 (0.35) | CRHR1KMT2AHPGDMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1200943-C | Organometallic acyl-aryl phosphine | CIBA SC HOLDING AG (CH) | 2005-05-11 | — | — | CN | disclosed |
| CN-1308081-A | Organometallic acyl-aryl phosphine | CIBA SC HOLDING AG (CH) | 2001-08-15 | — | — | CN | disclosed |