Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.31 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MPO | P05164 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27194792 | 0.88 | BCL2L1 (0.40) | KMT2AALDH1A1HPGDHSD17B10L3MBTL1 | |
| SCHEMBL27483932 | 0.86 | CYP2C9 (0.33) | CYP3A4CYP2C9KMT2AKDM4EALDH1A1 | |
| SCHEMBL28049095 | 0.83 | L3MBTL1 (0.40) | CYP3A4CYP2C9KMT2AKDM4EALDH1A1 | |
| SCHEMBL27499051 | 0.80 | NFE2L2 (0.35) | KMT2AALDH1A1HPGDMEN1LMNA | |
| SCHEMBL27499973 | 0.80 | ABCB1 (0.37) | CYP3A4CYP2C9KMT2AKDM4EALDH1A1 | |
| SCHEMBL27554102 | 0.78 | CRHR1 (0.36) | KMT2AKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL28221660 | 0.77 | RAB9A (0.34) | KDM4ETDP1LMNAPTGS2CRHR1 | |
| SCHEMBL615242 | 0.77 | LMNA (0.37) | KMT2AKDM4EHPGDL3MBTL1MEN1 | |
| SCHEMBL28781833 | 0.75 | LMNA (0.36) | KMT2AKDM4EHPGDL3MBTL1MEN1 | |
| Ammonia Solution, Strong SCHEMBL2909573 | 0.75 | LMNA (0.36) | KMT2AKDM4EALDH1A1HPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1200943-C | Organometallic acyl-aryl phosphine | CIBA SC HOLDING AG (CH) | 2005-05-11 | — | — | CN | disclosed |
| CN-1308081-A | Organometallic acyl-aryl phosphine | CIBA SC HOLDING AG (CH) | 2001-08-15 | — | — | CN | disclosed |