Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KLK7 | P49862 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7180203 | 0.96 | TDP1 (0.41) | TDP1L3MBTL1KMT2ACYP3A4MAPT | |
| SCHEMBL27486327 | 0.90 | CA12 (0.45) | TDP1L3MBTL1KMT2AMEN1ALDH1A1 | |
| SCHEMBL27554103 | 0.88 | KMT2A (0.46) | TDP1L3MBTL1KMT2ACYP3A4MAPT | |
| SCHEMBL27500594 | 0.85 | ALDH1A1 (0.41) | TDP1L3MBTL1KMT2ACYP3A4MAPT | |
| SCHEMBL27554209 | 0.85 | MMP8 (0.50) | TDP1L3MBTL1KMT2ACYP3A4MAPT | |
| SCHEMBL7177767 | 0.84 | TDP1 (0.46) | TDP1L3MBTL1KMT2ACYP3A4MAPT | |
| SCHEMBL7183694 | 0.84 | KMT2A (0.45) | TDP1L3MBTL1KMT2ACYP3A4MAPT | |
| SCHEMBL7187851 | 0.84 | CA12 (0.45) | L3MBTL1KMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL27519981 | 0.84 | KMT2A (0.40) | TDP1L3MBTL1KMT2ACYP3A4MAPT | |
| SCHEMBL27561211 | 0.83 | KMT2A (0.41) | TDP1L3MBTL1KMT2ACYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1200943-C | Organometallic acyl-aryl phosphine | CIBA SC HOLDING AG (CH) | 2005-05-11 | — | — | CN | disclosed |
| CN-1308081-A | Organometallic acyl-aryl phosphine | CIBA SC HOLDING AG (CH) | 2001-08-15 | — | — | CN | disclosed |