Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB1 | P20618 | 1/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.30 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27557752 | 0.87 | NR1H2 (0.40) | PSMB1PSMB5NR1H2 | |
| SCHEMBL27557773 | 0.84 | PSMB1 (0.42) | PSMB1PSMB5NR1H2AURKAAURKB | |
| SCHEMBL1924874 | 0.83 | PTGS2 (0.38) | PSMB5 | |
| SCHEMBL27558034 | 0.83 | NR1H2 (0.36) | PSMB1PSMB5NR1H2AURKAAURKB | |
| SCHEMBL1925572 | 0.79 | PTGS2 (0.37) | PSMB1PSMB5NR1H2AURKAAURKB | |
| SCHEMBL1924476 | 0.79 | PSMB1 (0.35) | PSMB1PSMB5NR1H2AURKAAURKB | |
| SCHEMBL1924339 | 0.76 | PTGS2 (0.38) | — | |
| SCHEMBL1924698 | 0.76 | PIK3CD (0.41) | — | |
| SCHEMBL27538953 | 0.76 | NR1H2 (0.33) | PSMB1PSMB5NR1H2AURKAAURKB | |
| SCHEMBL27535490 | 0.76 | KMT2A (0.33) | PSMB1PSMB5NR1H2AURKAAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1304379-C | Water-soluble phenylpyridazine compounds and compositions containing the same | KOWA CO (JP) | 2007-03-14 | — | — | CN | disclosed |
| CN-1759103-A | Water-soluble phenylpyridazine derivative and medicine containing the same | KOWA CO (JP) | 2006-04-12 | — | — | CN | disclosed |
| CN-1558903-A | Water-soluble phenylpyridazine derivative and drug containing the same | ������������ʽ���� | 2004-12-29 | — | — | CN | disclosed |