Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 4/20 | 0.36 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | AKT2 | P31751 | 1/20 | 0.30 |
| ▸ | TOP2A | P11388 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27557752 | 0.86 | NR1H2 (0.40) | NR1H2PSMB1PSMB5 | |
| SCHEMBL27557773 | 0.86 | PSMB1 (0.42) | NR1H2PSMB1PSMB5AURKAAURKB | |
| SCHEMBL27535490 | 0.83 | KMT2A (0.33) | NR1H2PSMB1PSMB5AURKAAURKB | |
| SCHEMBL27538953 | 0.83 | NR1H2 (0.33) | NR1H2PSMB1PSMB5AURKAAURKB | |
| SCHEMBL27557708 | 0.83 | PSMB1 (0.35) | NR1H2PSMB1PSMB5AURKAAURKB | |
| SCHEMBL27558003 | 0.81 | PSMB1 (0.39) | NR1H2PSMB1PSMB5EGFRAURKA | |
| SCHEMBL1925572 | 0.81 | PTGS2 (0.37) | NR1H2PSMB1PSMB5AURKAAURKB | |
| SCHEMBL1924476 | 0.81 | PSMB1 (0.35) | NR1H2PSMB1PSMB5AURKAAURKB | |
| SCHEMBL27575783 | 0.80 | PSMB1 (0.36) | NR1H2PSMB1PSMB5EGFRDPP4 | |
| SCHEMBL27643377 | 0.79 | PSMB1 (0.37) | NR1H2PSMB1PSMB5EGFRAURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1304379-C | Water-soluble phenylpyridazine compounds and compositions containing the same | KOWA CO (JP) | 2007-03-14 | — | — | CN | disclosed |
| CN-1759103-A | Water-soluble phenylpyridazine derivative and medicine containing the same | KOWA CO (JP) | 2006-04-12 | — | — | CN | disclosed |
| CN-1558903-A | Water-soluble phenylpyridazine derivative and drug containing the same | ������������ʽ���� | 2004-12-29 | — | — | CN | disclosed |