Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB1 | P20618 | 1/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 5/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27557752 | 0.88 | NR1H2 (0.40) | PSMB1PSMB5NR1H2 | |
| SCHEMBL27558034 | 0.86 | NR1H2 (0.36) | PSMB1PSMB5ALDH1A1MAPTAURKA | |
| SCHEMBL27557708 | 0.84 | PSMB1 (0.35) | PSMB1PSMB5AURKAAURKBNR1H2 | |
| SCHEMBL1925572 | 0.82 | PTGS2 (0.37) | PSMB1PSMB5AURKAAURKBKMT2A | |
| SCHEMBL1924476 | 0.82 | PSMB1 (0.35) | PSMB1PSMB5ALDH1A1AURKAAURKB | |
| SCHEMBL1924698 | 0.80 | PIK3CD (0.41) | ALDH1A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1924339 | 0.80 | PTGS2 (0.38) | SMN1; SMN2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL27538953 | 0.79 | NR1H2 (0.33) | PSMB1PSMB5AURKAAURKBKMT2A | |
| SCHEMBL27535490 | 0.79 | KMT2A (0.33) | PSMB1PSMB5AURKAAURKBKMT2A | |
| SCHEMBL27575774 | 0.76 | PSMB1 (0.42) | PSMB1PSMB5ALDH1A1SMN1; SMN2PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1304379-C | Water-soluble phenylpyridazine compounds and compositions containing the same | KOWA CO (JP) | 2007-03-14 | — | — | CN | disclosed |
| CN-1759103-A | Water-soluble phenylpyridazine derivative and medicine containing the same | KOWA CO (JP) | 2006-04-12 | — | — | CN | disclosed |
| CN-1558903-A | Water-soluble phenylpyridazine derivative and drug containing the same | ������������ʽ���� | 2004-12-29 | — | — | CN | disclosed |