SCHEMBL2755848

SCHEMBL2755848

NC(=O)Nc1ccc(Br)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PEPD P12955 1/20 0.64
ALDH1A1 P00352 3/20 0.61
MEN1 O00255 3/20 0.61
KMT2A Q03164 3/20 0.61
NPC1 O15118 3/20 0.61
MAPT P10636 2/20 0.57
GAA P10253 1/20 0.57
GFER P55789 1/20 0.57
MAOA P21397 1/20 0.57
MAOB P27338 1/20 0.57
LMNA P02545 2/20 0.55
F13A1 P00488 2/20 0.55
TGM2 P21980 2/20 0.55
KIF11 P52732 1/20 0.55
TGM1 P22735 1/20 0.55
TGM3 Q08188 1/20 0.55
GRIN2D O15399 1/20 0.53
GRIN3B O60391 1/20 0.53
GRIN1 Q05586 1/20 0.53
GRIN2A Q12879 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28052564 0.98 PEPD (0.61) PEPDALDH1A1MEN1KMT2ANPC1
SCHEMBL5062623 0.87 PEPD (0.80) PEPDALDH1A1MEN1KMT2ANPC1
SCHEMBL28813739 0.87 CA1 (0.60) PEPDALDH1A1MEN1KMT2ANPC1
SCHEMBL8993463 0.80 MAOA (0.83) MEN1KMT2ANPC1MAPTMAOA
SCHEMBL4100266 0.80 MEN1 (0.50) ALDH1A1MEN1KMT2ANPC1MAPT
SCHEMBL1322717 0.78 PEPD (1.00) PEPDALDH1A1MEN1KMT2ANPC1
SCHEMBL5536751 0.78 PEPD (0.67) PEPDALDH1A1MEN1KMT2ANPC1
SCHEMBL6879129 0.78 MAPT (0.70) PEPDALDH1A1MEN1KMT2ANPC1
SCHEMBL934994 0.78 MAOA (0.65) ALDH1A1MEN1KMT2ANPC1MAPT
SCHEMBL2098478 0.78 MEN1 (0.64) ALDH1A1MEN1KMT2ANPC1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 152 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119708623-A Heat stabilizer and preparation method thereof 西尼尔(山东)新材料科技有限公司 2025-03-28 CN claimed
EP-2638900-B1 DRUG FOR TREATING LIVER LESIONS CAUSED BY THE ACTION OF CHEMICAL OR BIOLOGICAL AGENTS TETS VIKTOR VENIAMINOVICH (RU) 2019-05-15 EP claimed
CN-107312731-A One plant of triclocarban degradation bacteria and its application 中国科学院生态环境研究中心 2017-11-03 CN claimed
US-8999959-B2 Drug for treating liver lesions caused by the action of chemical or biological agents Tets, Viktor Veniaminovich (RU) 2015-04-07 US claimed
CN-101993416-A Quinoline compound and preparation method thereof, medicament combination containing compound and application of compound SHANGHAI INST MATERIA MEDICA 2011-03-30 CN claimed
CN-1146320-C Enhancement of seed yield of soybeans by substituted benzoyl urea 尤尼罗亚尔化学公司 2004-04-21 CN claimed
CN-1406110-A Enhancement of seed/fruit/nut yield from flowering plants UNIROYAL CHEM CO INC (US) 2003-03-26 CN claimed
CN-1272040-A Enhancement of seed yield of soybeans by substituted benzoyl urea UNIROYAL CHEM CO INC (US) 2000-11-01 CN claimed
CN-1221316-A Benzoylurea insecticides on gene-modified Bt cotton UNIROYAL CHEM CO INC (US) 1999-06-30 CN claimed
US-5374608-A Compositions containing adducts and surfactants UNION OIL COMPANY OF CALIFORNIA (US) 1994-12-20 US claimed
US-5288692-A Systemic herbicides and methods of use UNION OIL COMPANY OF CALIFORNIA (US) 1994-02-22 US claimed
US-20250205219-A1 TARGETED DEGRADATION OF VAV1 MONTE ROSA THERAPEUTICS AG (CH) 2025-06-26 US disclosed
CN-119708623-A Heat stabilizer and preparation method thereof 西尼尔(山东)新材料科技有限公司 2025-03-28 CN disclosed
US-12257247-B2 Targeted degradation of VAV1 MONTE ROSA THERAPEUTICS AG (CH) 2025-03-25 US disclosed
US-20240400499-A1 NOVEL AMINO ACID DERIVATIVES PEPTIDREAM INC (JP) 2024-12-05 US disclosed
EP-0219923-A1 Antibiotic derivatives, their production and use Takeda Chemical Industries, Ltd. (JP) 1987-04-29 EP disclosed
US-4657632-A CONTAINING A THIOUREA AND A UREA COMPOUND TECHNO INSTRUMENTS INVESTMENTS 1983 LTD. (IL) 1987-04-14 US disclosed
EP-0216531-A1 Use of immersion tin and tin alloys as a bonding medium for multilayer circuits TECHNO INSTRUMENTS INVESTMENTS 1983 LTD. (IL) 1987-04-01 EP disclosed
EP-0191989-A1 Antibiotic isoxazole derivatives, their production and use Takeda Chemical Industries, Ltd. (JP) 1986-08-27 EP disclosed
CN-85101497-A Process for the preparation of N-aryl-3-aryl-4, 5-dihydro-1H-pyrazole-1-carboxamides 1986-07-16 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12257247-B2 Targeted degradation of VAV1 VAV1, KRAS, CBL PEPD 4711/4885ALDH1A1 3624/4885MEN1 1386/4885
US-20250205219-A1 TARGETED DEGRADATION OF VAV1 VAV1, KRAS, CBL PEPD 4711/4885ALDH1A1 3624/4885MEN1 1386/4885
US-20240400499-A1 NOVEL AMINO ACID DERIVATIVES BCAT1, BCAT2, PELP1 PEPD 11/4885ALDH1A1 4472/4885MEN1 4354/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.